M
Mark Lakshmanan
Researcher at Eli Lilly and Company
Publications - 36
Citations - 2145
Mark Lakshmanan is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Dulaglutide & Hazard ratio. The author has an hindex of 14, co-authored 31 publications receiving 1680 citations.
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Journal ArticleDOI
Teriparatide for Acceleration of Fracture Repair in Humans: A Prospective, Randomized, Double-Blind Study of 102 Postmenopausal Women With Distal Radial Fractures
Per Aspenberg,Harry K. Genant,Torsten Johansson,Antonio J. Nino,Kyoungah See,Kelly Krohn,Pedro A García-Hernández,Christopher P Recknor,Thomas A. Einhorn,Gail P Dalsky,Bruce H. Mitlak,Anke Fierlinger,Mark Lakshmanan +12 more
TL;DR: The shortened time to healing for teriparatide 20 µg compared with placebo still may suggest that fracture repair can be accelerated by teriparkinide, but this result should be interpreted with caution and warrants further study.
Journal ArticleDOI
Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial
Katherine R. Tuttle,Mark Lakshmanan,Brian Rayner,Robert S. Busch,Alan G. Zimmermann,D. Bradley Woodward,Fady T. Botros +6 more
TL;DR: Dulaglutide is a long-acting glucagon-like peptide-1 receptor agonist that is not cleared by the kidneys, and confers a lower risk of hypoglycaemia than does insulin, and is assessed in patients with type 2 diabetes and moderate-to-severe chronic kidney disease.
Journal ArticleDOI
Efficacy and Safety of Dulaglutide Added Onto Pioglitazone and Metformin Versus Exenatide in Type 2 Diabetes in a Randomized Controlled Trial (AWARD-1)
Carol Wysham,Thomas Blevins,Richard Arakaki,Gildred Colon,Pedro Garcia,Charles Atisso,Debra Kuhstoss,Mark Lakshmanan +7 more
TL;DR: Both once-weekly dulaglutide doses demonstrated superior glycemic control versus placebo and exenatide with an acceptable tolerability and safety profile in type 2 diabetic patients.
Journal ArticleDOI
Adverse events reported by postmenopausal women in controlled trials with raloxifene.
TL;DR: In this paper, the incidence and severity of adverse events in postmenopausal women treated with raloxifene compared with placebo, hormone replacement therapy (HRT), or unopposed estrogen.
Journal ArticleDOI
Design and baseline characteristics of participants in the Researching cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) trial on the cardiovascular effects of dulaglutide
Hertzel C. Gerstein,Helen M. Colhoun,Gilles R. Dagenais,Rafael Diaz,Mark Lakshmanan,Prem Pais,Jeffrey L. Probstfield,Matthew C. Riddle,Lars Rydén,Denis Xavier,Charles Atisso,Alvaro Avezum,Jan Basile,Namsik Chung,Ignacio Conget,William C. Cushman,Edward Franek,Nicolae Hancu,Markolf Hanefeld,Shaun Holt,Petr Jansky,Matyas Keltai,Fernando Lanas,Lawrence A. Leiter,Patricio Lopez-Jaramillo,Ernesto Germán Cardona-Muñoz,Valdis Pirags,Nana Pogosova,Peter J Raubenheimer,Jonathan E. Shaw,Wayne Huey-Herng Sheu,Theodora Temelkova-Kurktschiev +31 more
TL;DR: The REWIND trial's international scope, high proportion of women, highportion of people without prior cardiovascular disease and inclusion of participants whose mean baseline HbA1c was 7.3% suggests that its cardiovascular and safety findings will be directly relevant to the typical middle‐aged patient seen in general practice throughout the world.