M
Mark R. Brown
Researcher at University of Georgia
Publications - 100
Citations - 6745
Mark R. Brown is an academic researcher from University of Georgia. The author has contributed to research in topics: Aedes aegypti & Midgut. The author has an hindex of 45, co-authored 95 publications receiving 5947 citations. Previous affiliations of Mark R. Brown include Texas A&M University.
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Journal ArticleDOI
Signaling and function of insulin-like peptides in insects
Qi Wu,Mark R. Brown +1 more
TL;DR: An integrated summary of the efforts to characterize the distribution of ILPs in insects and to define this pathway and its functions in Drosophila is offered and a few considerations for future studies of ILP endocrinology in insects are offered.
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Mosquitoes rely on their gut microbiota for development.
TL;DR: It is suggested that three mosquito species spanning the breadth of the Culicidae depend on their gut microbiome for development, and pyrosequencing of 16S rRNA provides new insights about the acquisition and structure of bacterial communities in mosquitoes.
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Neuropeptides and Peptide Hormones in Anopheles gambiae
TL;DR: Regulatory peptides from 35 genes annotated from the Anopheles gambiae genome likely coordinate growth and reproduction of its vector, A. gambiae, as in Drosophila melanogaster, Caenorhabditis elegans, and mammals.
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Identification of a Drosophila brain-gut peptide related to the neuropeptide Y family.
TL;DR: In situ hybridization and immunocytochemistry showed that Drosophila NPF was expressed in the brain and midgut of fly larvae and adults, and can be processed into an amidated NPF with 36 residues that is related to invertebrate NPF's and the neuropeptide Y family of vertebrates.
Journal ArticleDOI
An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegypti
Mark R. Brown,Kevin Clark,Monika Gulia,Zhangwu Zhao,Stephen F. Garczynski,Joe W. Crim,Richard J. Suderman,Michael R. Strand +7 more
TL;DR: This article showed that synthetic ILP3 dose-dependently stimulated yolk uptake by oocytes and ecdysteroid production by the ovaries at lower concentrations than bovine insulin.