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Mark Richards

Researcher at National University of Singapore

Publications -  50
Citations -  3330

Mark Richards is an academic researcher from National University of Singapore. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 23, co-authored 50 publications receiving 2974 citations. Previous affiliations of Mark Richards include University of Otago & Nanyang Polytechnic.

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Human feeders support prolonged undifferentiated growth of human inner cell masses and embryonic stem cells.

TL;DR: It is shown that human fetal and adult fibroblast feeders support prolonged undifferentiated HES cell growth of existing cell lines and are superior to cell-free matrices supplemented with human or MEF feeder–conditioned medium.
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The Transcriptome Profile of Human Embryonic Stem Cells as Defined by SAGE

TL;DR: The overlapping similarities and differences in gene expression profiles of human and mouse ES cells provide a foundation for a detailed and concerted dissection of the molecular and cellular mechanisms governing their pluripotency, directed differentiation into specific cell types, and extended ability for self‐renewal.
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Comparative Evaluation of Various Human Feeders for Prolonged Undifferentiated Growth of Human Embryonic Stem Cells

TL;DR: It is reported that two adult skin fibroblast cell lines established in‐house from abdominal skin biopsies supported prolonged undifferentiated hES cell growth for over 30 weekly passages in culture.
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Comparative growth behaviour and characterization of stem cells from human Wharton's jelly.

TL;DR: Wharton's jelly stem cells are not as pluripotent as hESC but widely multipotent, and have the advantages of being able to be scaled up easily and not inducing teratomas.