M
Mark S. Gibson
Researcher at Institute for Animal Health
Publications - 11
Citations - 307
Mark S. Gibson is an academic researcher from Institute for Animal Health. The author has contributed to research in topics: Gene & Locus (genetics). The author has an hindex of 8, co-authored 10 publications receiving 248 citations. Previous affiliations of Mark S. Gibson include Universidade Nova de Lisboa.
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Journal ArticleDOI
Chicken Interferon-Inducible Transmembrane Protein 3 Restricts Influenza Viruses and Lyssaviruses In Vitro
Sarah E. Smith,Mark S. Gibson,Rachael S. Wash,Francesca Ferrara,Edward Wright,Nigel J. Temperton,Paul Kellam,Paul Kellam,Mark Fife +8 more
TL;DR: The chicken IFITM3 protein restricts cell infection by influenza A viruses and lyssaviruses to a similar level as its human orthologue and is functional in chicken cells, suggestingIFITM proteins may provide a crucial barrier for zoonotic infections.
Journal ArticleDOI
Lipid and Non-lipid Factors Affecting Macrophage Dysfunction and Inflammation in Atherosclerosis.
TL;DR: Using oxidized low density lipoproteins and its oxidized cholesteryl esters and phospholipid constituents to stimulate macrophage has been hugely valuable, however there is now an argument that only working with low complexity lipid species can deliver the most useful information to guide therapies aimed at controlling atherosclerosis and cardiovascular complications.
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Prospects for understanding immune-endocrine interactions in the chicken.
Pete Kaiser,Zhiguang Wu,Lisa Rothwell,Mark Fife,Mark S. Gibson,Tuang-Yeow Poh,A. Shini,Wayne L. Bryden,Shaniko Shini +8 more
TL;DR: Differences between immune gene repertoires of birds and mammals, particularly those known to play a role in immune-endocrine interactions in mammals are discussed, and recent findings on the expression of their receptors are reviewed.
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The evolution of the natural killer complex; a comparison between mammals using new high-quality genome assemblies and targeted annotation.
John C. Schwartz,Mark S. Gibson,Mark S. Gibson,Dorothea Heimeier,Sergey Koren,Adam M. Phillippy,Derek M. Bickhart,Timothy P L Smith,Juan F. Medrano,John A. Hammond +9 more
TL;DR: Targeted genome enrichment in cattle identified varying levels of allelic polymorphism between the NKC genes concentrated in the predicted extracellular ligand-binding domains, suggesting that this diversity influences individual immune responses and may impact on differential outcomes of pathogen infection and vaccination.
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Identification of chicken granulocyte colony-stimulating factor (G-CSF/CSF3): the previously described myelomonocytic growth factor is actually CSF3
TL;DR: Full-length sequencing of the entire region and thorough, detailed analysis of the coding region confirmed that the MGF gene lay within this sequence gap, and therefore that it should be renamed CSF3.