M
Mark T. Kearns
Researcher at Denver Health Medical Center
Publications - 10
Citations - 574
Mark T. Kearns is an academic researcher from Denver Health Medical Center. The author has contributed to research in topics: Macrophage & Lung injury. The author has an hindex of 8, co-authored 9 publications receiving 402 citations. Previous affiliations of Mark T. Kearns include University of Colorado Denver & University of Colorado Boulder.
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Journal ArticleDOI
Fas Determines Differential Fates of Resident and Recruited Macrophages during Resolution of Acute Lung Injury
William J. Janssen,Lea Barthel,Alaina Muldrow,Rebecca E Oberley-Deegan,Mark T. Kearns,Claudia Jakubzick,Peter M. Henson +6 more
TL;DR: It is shown that Fas-induced apoptosis of recruited macrophages is essential for complete resolution of ALI, and the role of Fas in determining macrophage fate during resolving ALI is studied.
Journal ArticleDOI
Experiences of Latinx Individuals Hospitalized for COVID-19: A Qualitative Study.
Lilia Cervantes,Marlene Martin,Maria G. Frank,Julia F. Farfan,Mark T. Kearns,Luis Rubio,Allison Tong,Allison Tong,Andrea Matus Gonzalez,Andrea Matus Gonzalez,Claudia Camacho,Adriana Collings,William Mundo,Neil R. Powe,Alicia Fernandez +14 more
TL;DR: In this paper, the authors used semistructured phone interviews of 60 Latinx adults who survived a COVID-19 hospitalization in public hospitals in San Francisco, California, and Denver, Colorado from March 2020 to July 2020.
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The Causal Role of IL-4 and IL-13 in Schistosoma mansoni Pulmonary Hypertension.
Rajesh Kumar,Claudia Mickael,Jacob J. Chabon,Liya Gebreab,Alleluiah Rutebemberwa,Alexandra Rodriguez Garcia,Daniel E. Koyanagi,Linda Sanders,Aneta Gandjeva,Mark T. Kearns,Lea Barthel,William J. Janssen,Thais Mauad,Angela Bandeira,Eric P. Schmidt,Rubin M. Tuder,Brian B. Graham +16 more
TL;DR: Combined IL-4 and IL-13 deficiency is required for protection against TGF-β-induced pulmonary vascular disease after Schistosoma exposure, and targeted inhibition of this pathway is a potential novel therapeutic approach for patients with schistosomiasis-associated PAH.
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Safety and Outcomes of Prolonged Usual Care Prone Position Mechanical Ventilation to Treat Acute Coronavirus Disease 2019 Hypoxemic Respiratory Failure.
Ivor S. Douglas,Ivor S. Douglas,Chester A Rosenthal,Diandra D Swanson,Terra D. Hiller,Judy Oakes,Jamie Bach,Christopher Whelchel,Jennifer Pickering,Tobias George,Mark T. Kearns,Mark T. Kearns,Michael Hanley,Michael Hanley,Kara J. Mould,Sarah Roark,Sarah Roark,Jason Mansoori,Jason Mansoori,Anuj B. Mehta,Eric P. Schmidt,Eric P. Schmidt,Anna Neumeier,Anna Neumeier +23 more
TL;DR: In this article, the authors evaluated the safety and associated clinical outcomes for patients with acute respiratory distress syndrome treated with prolonged prone position ventilation without daily repositioning, and concluded that such ventilation is feasible and relatively safe.
Journal ArticleDOI
Circulating hematopoietic progenitor cells are decreased in COPD.
William J. Janssen,Zulma X. Yunt,Alaina Muldrow,Mark T. Kearns,Angela Kloepfer,Lea Barthel,Donna L. Bratton,Russell P. Bowler,Peter M. Henson +8 more
TL;DR: HPC levels are reduced in subjects with COPD and correlate with emphysema phenotype and severity of obstruction, which may disrupt maintenance of the capillary endothelium, thereby contributing to the pathogenesis of COPD.