M
Markus Neubauer
Researcher at Danube University Krems
Publications - 11
Citations - 41
Markus Neubauer is an academic researcher from Danube University Krems. The author has contributed to research in topics: Chemistry & Proinflammatory cytokine. The author has an hindex of 2, co-authored 11 publications receiving 19 citations.
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Journal ArticleDOI
The Effect of Blood-Derived Products on the Chondrogenic and Osteogenic Differentiation Potential of Adipose-Derived Mesenchymal Stem Cells Originated from Three Different Locations.
Markus Neubauer,Olga Kuten,Christoph Stotter,Karina Kramer,Andrea De Luna,Thomas Muellner,Zsombor Lacza,Stefan Nehrer +7 more
TL;DR: Blood product preparation method, type of anticoagulant, differentiation time, and blood product concentration have a significant influence on stem cell viability and the differentiation potential, favouring no use of antICOagulation, shorter differentiation periods, and lower blood product concentrations.
Journal ArticleDOI
Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous blood products.
Alexander Otahal,Olga Kuten-Pella,Karina Kramer,Markus Neubauer,Zsombor Lacza,Stefan Nehrer,Andrea De Luna +6 more
TL;DR: An isolation protocol is developed for EVs from CPRP and hypACT that can also deplete lipoproteins, which are often co-isolated in EV research due to shared physical properties and to gain insights into the functional repertoire conveyed via EV-associated miRNAs.
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Bone-marrow-aspirate-concentrate for chondral defects: surgical techniques, clinical applications and basic science
TL;DR: This article aims to bridge the gap by providing comprehensive information for practicing surgeons to ease patient selection and clinical application of BMAC for chondral defects.
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Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes within an Inflammation Model
Alexander Otahal,Karina Kramer,Olga Kuten-Pella,Lukas B. Moser,Markus Neubauer,Zsombor Lacza,Stefan Nehrer,Andrea De Luna +7 more
TL;DR: In this paper, a co-culture system of primary OA chondrocytes and activated M1 macrophages was developed to model an OA joint in order to observe the effects of EVs in modulating the inflammatory environment.
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Regenerative Potential of Blood-Derived Products in 3D Osteoarthritic Chondrocyte Culture System.
TL;DR: The regenerative potential of two types of platelet-rich plasma (PRP), prepared in the presence of EDTA (EPRP) and citrate (CPRP)), and an alternative blood product-hyperacute serum (hypACT) was evaluated using a 3D osteoarthritic chondrocyte pellet model by assessing the metabolic cell activity, cartilage-related gene expression and extracellular matrix deposition within the pellets.