M
Marla B. Feller
Researcher at Helen Wills Neuroscience Institute
Publications - 110
Citations - 8817
Marla B. Feller is an academic researcher from Helen Wills Neuroscience Institute. The author has contributed to research in topics: Retina & Retinal waves. The author has an hindex of 42, co-authored 99 publications receiving 7923 citations. Previous affiliations of Marla B. Feller include University of California & National Institutes of Health.
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Mechanisms underlying spontaneous patterned activity in developing neural circuits
TL;DR: This research suggests that developing neural circuits exhibit transient and tunable features that maintain a source of correlated activity during crucial stages of development.
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Mechanisms Underlying Development of Visual Maps and Receptive Fields
TL;DR: A major goal now is to determine how axon guidance cues and a growing list of other molecules cooperate with spontaneous and visually evoked activity to give rise to the circuits underlying precise receptive field tuning and orderly visual maps.
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Requirement for cholinergic synaptic transmission in the propagation of spontaneous retinal waves.
TL;DR: The results indicate that the major source of synaptic input to retinal ganglion cells is a system of cholinergic amacrine cells, whose activity is required for wave propagation in the developing retina.
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Competition in Retinogeniculate Patterning Driven by Spontaneous Activity
TL;DR: Interocular competition driven by endogenous retinal activity determines the pattern of eye-specific connections from retina to LGN, demonstrating that spontaneous activity can produce highly stereotyped patterns of connections before the onset of visual experience.
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Retinotopic map refinement requires spontaneous retinal waves during a brief critical period of development.
TL;DR: Wave dynamics and retinocollicular projections in mice lacking the beta2 subunit of the nicotinic acetylcholine receptor are examined, finding that spontaneous retinal waves that correlate RGC activity are required for retinotopic map remodeling during a brief early critical period.