M
Marshall E. Bloom
Researcher at Rocky Mountain Laboratories
Publications - 116
Citations - 5039
Marshall E. Bloom is an academic researcher from Rocky Mountain Laboratories. The author has contributed to research in topics: Mink & Aleutian Mink Disease Virus. The author has an hindex of 39, co-authored 112 publications receiving 4660 citations. Previous affiliations of Marshall E. Bloom include University of Copenhagen & National Institutes of Health.
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Journal ArticleDOI
Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain.
Bruce Chesebro,Richard E. Race,Kathy Wehrly,J. Nishio,Marshall E. Bloom,David Lechner,Sven Bergstrom,Ken Robbins,Leonard W. Mayer,Leonard W. Mayer,Jerry M. Keith,Claude F. Garon,Ashley T. Haase +12 more
TL;DR: It is reported here that a complementary DNA clone representing PrP27–30 was obtained from scrapie-infected mouse brain; the DNA sequence of this clone could be translated into a protein that matches exactly the published sequence of PrP 27–30.
Journal ArticleDOI
Inhibition of Interferon-Stimulated JAK-STAT Signaling by a Tick-Borne Flavivirus and Identification of NS5 as an Interferon Antagonist
Sonja M. Best,Keely L. Morris,Jeffrey G. Shannon,Shelly J. Robertson,Dana N. Mitzel,Gregory S. Park,Elena F. Boer,James B. Wolfinbarger,Marshall E. Bloom +8 more
TL;DR: Examination of interactions between NS5 and cellular proteins revealed that NS5 associated with IFN-α/β and -γ receptor complexes, which indicates that this protein may have a significant role in viral pathogenesis.
Journal ArticleDOI
Parvovirus infections in wild carnivores.
TL;DR: In this review article the knowledge about infections of free-ranging or captive carnivores with the feline parvoviruses, feline panleukopenia virus, and canineParvovirus, including the antigenic types CPV-2a and -2b, as well as Aleutian disease of mink virus and minute virus of canines are summarized.
Journal ArticleDOI
The NS5 Protein of the Virulent West Nile Virus NY99 Strain Is a Potent Antagonist of Type I Interferon-Mediated JAK-STAT Signaling
Maudry Laurent-Rolle,Elena F. Boer,Kirk J. Lubick,James B. Wolfinbarger,Aaron B. Carmody,Barry Rockx,Wen Jun Liu,Joseph Ashour,W. Lesley Shupert,Michael R. Holbrook,Michael R. Holbrook,Alan D.T. Barrett,Peter W. Mason,Peter W. Mason,Marshall E. Bloom,Adolfo García-Sastre,Alexander A. Khromykh,Sonja M. Best +17 more
TL;DR: It is reported that NS5 from the virulent NY99 strain of WNV prevented pY-STAT1 accumulation, suppressedIFN-dependent gene expression, and rescued the growth of a highly IFN-sensitive virus (Newcastle disease virus) in the presence of IFN, suggesting that this protein can function as an efficient IFN antagonist.
Journal ArticleDOI
Characterization of Aleutian disease virus as a parvovirus.
TL;DR: Data suggest that Aleutian disease virus is a nondefective parvovirus, which has a single non-complementary strand with a molecular weight of about 1.4 X 10(6).