M
Martin Buck
Researcher at Imperial College London
Publications - 235
Citations - 9695
Martin Buck is an academic researcher from Imperial College London. The author has contributed to research in topics: RNA polymerase & Transcription (biology). The author has an hindex of 51, co-authored 228 publications receiving 8972 citations. Previous affiliations of Martin Buck include Federal University of Paraná & University of Sussex.
Papers
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The bacterial enhancer-dependent sigma(54) (sigma(N)) transcription factor.
TL;DR: The initiation of transcription is a complex process involving many different steps, and many have been exploited by bacteria to give rise to sophisticated regulatory mechanisms that allow the cell to adapt to changing environment.
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Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology
TL;DR: An orthogonal AND gate in Escherichia coli is constructed using a novel hetero-regulation module from Pseudomonas syringae and demonstrated to be modular by applying new regulated promoters to the inputs, and connecting the output to a NOT gate module to produce a combinatorial NAND gate.
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Upstream activator sequences are present in the promoters of nitrogen fixation genes
TL;DR: It is shown that the positioning and orientation of the upstream sequence is not critical for promoter activity up to a distance of 2 kilobases (kb) and that the upstream sequences is itself transcriptionally inactive, probably acting in cis with the downstream sequences to produce a fully active promoter.
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In vivo studies on the interaction of RNA polymerase-sigma 54 with the Klebsiella pneumoniae and Rhizobium meliloti nifH promoters. The role of NifA in the formation of an open promoter complex.
Enrique Morett,Martin Buck +1 more
TL;DR: A model in which the fidelity of activation of sigma 54-dependent promoters relies on a weak activator-independent interaction of RNA polymerase-sigma 54 with the promoter is proposed.
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Managing membrane stress: the phage shock protein (Psp) response, from molecular mechanisms to physiology.
Nicolas Joly,Christoph Engl,Goran Jovanovic,Maxime Huvet,Tina Toni,Xia Sheng,Michael P. H. Stumpf,Martin Buck +7 more
TL;DR: Progress in understanding the mechanism of signal transduction by the membrane-bound Psp proteins, regulation of the psp gene-specific transcription activator and the cell biology of the Psp system is presented and discussed.