M
Martin E. Fernandez-Zapico
Researcher at Mayo Clinic
Publications - 231
Citations - 14148
Martin E. Fernandez-Zapico is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Pancreatic cancer & Transcription factor. The author has an hindex of 47, co-authored 205 publications receiving 12174 citations. Previous affiliations of Martin E. Fernandez-Zapico include University of Saint Mary & McGill University.
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'Look for the right mentor'. An interview with Prof. Manfred v. Singer.
TL;DR: Manfred V. Singer, a pioneer in the field of neuro-hormonal regulation of pancreatic exocrine secretion, is interviewed and points out key aspects of a successful mentor-mentee relationship.
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Never Conclude with a Negative Result, Explore All Possibilities before Changing Your Hypothesis
TL;DR: Catherine Figarella demonstrated that a similar phenomenon may occur in cystic fibrosis (CF) and has applied this knowledge of pancreatic zymogens to follow the evolution of the pancreatic disease in CF.
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A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition.
Isaac P. Horn,David L. Marks,Amanda N. Koenig,Tara L. Hogenson,Luciana L. Almada,Lauren E. Goldstein,Paola A. Romecin Duran,Renzo E. Vera,Anne M. Vrabel,Gaofeng Cui,Kari G. Rabe,William R. Bamlet,Georges Mer,Hugues Sicotte,Cheng Zhang,Hu Li,Gloria M. Petersen,Martin E. Fernandez-Zapico +17 more
TL;DR: In this paper, the authors investigated the biological significance of the p16-L16R mutant protein associated with high cancer occurrence and found that p16 protein was detected at lower levels in p16−L16−R than in wild-type (WT) p16.
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Number and Type of TET2 Mutations in Chronic Myelomonocytic Leukemia: Clinical and Prognostic Correlates
Mrinal M. Patnaik,Mohammad Faizan Zahid,Terra L. Lasho,Ezequiel J. Tolosa,Christy Finke,Curtis A. Hanson,Rhett P. Ketterling,Eric Solary,Keith D. Robertson,Naseema Gangat,Martin E. Fernandez-Zapico,Ayalew Tefferi +11 more
TL;DR: The number and type of TET2 mutations, with frame shift, non-sense, and missense variations considered pathogenic, and phenotypic and prognostic effects are described and examined in patients with chronic myelomonocytic leukemia.