Kari G. Rabe

TL;DR: Age, grade, stage, and functional status predict survival in patients with PNETs, and survival has improved over time, but this is not explained by earlier diagnosis or stage migration.

TL;DR: Families who fulfill AC-I criteria but who have no evidence of a DNA MMR defect do not share the same cancer incidence as families with HNPCC-Lynch syndrome, and the designation of "familial colorectal cancer type X" is suggested to describe this type of familial aggregation of coloreCTal cancer.

TL;DR: In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, this paper observed large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples.

TL;DR: Almost 1% of diabetes subjects aged > or =50 years will be diagnosed with pancreatic cancer within 3 years of first meeting criteria for diabetes, and the usefulness of new-onset diabetes as marker of early pancreaticcancer needs further evaluation.

TL;DR: Large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases.