M
Martin L. Yarmush
Researcher at Rutgers University
Publications - 714
Citations - 38094
Martin L. Yarmush is an academic researcher from Rutgers University. The author has contributed to research in topics: Transplantation & Bioartificial liver device. The author has an hindex of 91, co-authored 702 publications receiving 34591 citations. Previous affiliations of Martin L. Yarmush include University of Medicine and Dentistry of New Jersey & Shriners Hospitals for Children.
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Journal ArticleDOI
Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix
Basak E. Uygun,Alejandro Soto-Gutierrez,Alejandro Soto-Gutierrez,Hiroshi Yagi,Hiroshi Yagi,Maria Louisa Izamis,Maria Angela Guzzardi,Maria Angela Guzzardi,Carley Shulman,Jack M. Milwid,Naoya Kobayashi,Arno W. Tilles,Francois Berthiaume,Francois Berthiaume,Martin Hertl,Yaakov Nahmias,Yaakov Nahmias,Martin L. Yarmush,Martin L. Yarmush,Korkut Uygun +19 more
TL;DR: A novel approach to generate transplantable liver grafts using decellularized liver matrix that preserves the structural and functional characteristics of the native microvascular network, allowing efficient recellularization of the liver matrix with adult hepatocytes and subsequent perfusion for in vitro culture.
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Effect of cell–cell interactions in preservation of cellular phenotype: cocultivation of hepatocytes and nonparenchymal cells
TL;DR: Although the precise mechanisms by which nonparenchymal cells modulate the hepatocyte phenotype remain unelucidated, some new insights on the modes of cell signaling, the extent of cell–cell interaction, and the ratio of cell populations are noted.
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Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration.
TL;DR: Adult rat hepatocytes cultured in a collagen sandwich system maintained normal morphology and a physiological rate of albumin secretion for at least 42 days and provided a simple method for their long‐term maintenance.
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Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration.
TL;DR: It is suggested that simple manipulations of the configuration of extracellular elements can dramatically alter the behavior of cultured hepatocytes.
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Electroporation-Based Technologies for Medicine: Principles, Applications, and Challenges
TL;DR: This review describes the theory and current applications of electroporation in medicine and then discusses current challenges in Electroporation research and barriers to a more extensive spread of these clinical applications.