M
Martin Lotz
Researcher at Scripps Research Institute
Publications - 382
Citations - 33862
Martin Lotz is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Cartilage & Chondrocyte. The author has an hindex of 97, co-authored 343 publications receiving 30942 citations. Previous affiliations of Martin Lotz include Japan Agency for Medical Research and Development & University of California, San Diego.
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Journal Article
Interferon-gamma is a major regulator of C1-inhibitor synthesis by human blood monocytes.
Martin Lotz,Bruce L. Zuraw +1 more
TL;DR: It is demonstrated that IFN-gamma is a major regulator of monocyte C1INH production and may warrant consideration of IFN -gamma in the treatment of C1inH deficiency states.
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Interleukin‐6 and transforming growth factor‐β synergistically stimulate chondrosarcoma cell proliferation
Pierre-André Guerne,Martin Lotz +1 more
TL;DR: This study examines the regulation of Swarm rat chondrosarcoma cell proliferation in vitro and identified Transforming growth factor‐β (TGF‐β) as an essential serum component, since the mitogenic effect of sera was related to their TGF-β content and neutralized by antibody to TGF‐ β.
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Chondrocyte clusters adjacent to sites of cartilage degeneration have characteristics of progenitor cells.
Yoshiaki Hoshiyama,Shuhei Otsuki,Shuhei Oda,Yoshitaka Kurokawa,Mikio Nakajima,Tsuyoshi Jotoku,Ryuichi Tamura,Yoshinori Okamoto,Martin Lotz,Masashi Neo +9 more
TL;DR: Chondrocyte clusters adjacent to severe cartilage degeneration have specific characteristics, with progenitor and proliferative potential, according to Orthopaedic Research Society.
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Transthyretin deposition in articular cartilage: a novel mechanism in the pathogenesis of osteoarthritis.
Yukio Akasaki,Natàlia Reixach,Tokio Matsuzaki,Oscar Alvarez-Garcia,Merissa Olmer,Yukihide Iwamoto,Joel N. Buxbaum,Martin Lotz +7 more
TL;DR: This study undertook this study to define the dominant precursor and to determine whether the deposits affect chondrocyte functions, and to defined theAmyloid deposits.
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Activation of Urinary Kallikrein in Patients with Interstitial Cystitis
TL;DR: A potential pathophysiological role for the urinary kallikrein-kinin system is suggested by the prominent symptoms of bladder pain and urinary frequency in interstitial cystitis, and patients who underwent hydrodistention and subsequently experienced relief from the bladder symptoms had a decrease in urinary kanine levels.