M
Mary Jo Wick
Researcher at University of Gothenburg
Publications - 58
Citations - 3794
Mary Jo Wick is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Antigen & Immune system. The author has an hindex of 33, co-authored 55 publications receiving 3545 citations. Previous affiliations of Mary Jo Wick include Lund University.
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Bacterial strategies for overcoming host innate and adaptive immune responses
TL;DR: The spectrum of strategies used by microbes to avoid or provoke activation of the host's immune response are described as well as the current understanding of the role this immunomodulatory interference plays during microbial pathogenesis are described.
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The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion.
Michael T. Wilson,Cecilia Johansson,Danyvid Olivares-Villagómez,Avneesh K. Singh,Aleksandar K. Stanic,Chyung Ru Wang,Sebastian Joyce,Mary Jo Wick,Luc Van Kaer +8 more
TL;DR: It is indicated that in vivo activation of NKT cells leads to a dynamic response characterized by surface receptor down-modulation and expansion, which alters current understanding of N KT cell biology and should aid in the rational design ofNKT cell-based immunotherapies.
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Salmonella-Induced Apoptosis of Infected Macrophages Results in Presentation of a Bacteria-Encoded Antigen after Uptake by Bystander Dendritic Cells
Ulf Yrlid,Mary Jo Wick +1 more
TL;DR: It is shown that infection of bone marrow–derived macrophages with wild-type S. typhimurium results in presentation of epitopes derived from a bacteria-encoded antigen on major histocompatibility complex (MHC) class I and MHC class II molecules after internalization of apoptotic MΦ by bystander dendritic cells (DCs).
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The Innate Immune Response Differs in Primary and Secondary Salmonella Infection
TL;DR: These studies provide a coherent view of innate immunity to oral Salmonella infection, reveal novel sources of IFN-γ, and demonstrate that immune status influences the nature of the innate response.
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Early cellular responses to Salmonella infection: dendritic cells, monocytes, and more
TL;DR: Dendritic cells, monocytes, macrophages, and neutrophils are myeloid‐derived phagocytes critical to controlling bacterial infections, and these cells have complementary functions to ensure host survival.