Masa-aki Hattori

TL;DR: After exposure to increased LH and hCG levels in vivo and in vitro, LH receptors show an initial transient increase followed by a marked decrease and a prolonged depletion of LH receptor sites, suggesting that nucleotide-induced phosphorylation is related to activation of the catalytic cyclase unit.

TL;DR: Four kinds of cultured clonal cell line were established from estrogen-induced mammotropic pituitary tumor and among these newly established cell lines, MtT/Se was the smallest in size and showed estrogen-dependent proliferation and the many small secretory-like granules present in the cytoplasm of MtT-Se cells showed no immunocytochemically positive reaction for anterior pituitarian hormone.

TL;DR: The heterogeneity of avian pituitary LH was shown by means of isoelectric focusing and gel filtration studies coupled with radioimmunoassay, which indicated the presence of an LH with a molecular weight of 23,500–25,000 together with a component having double the molecular weight.

TL;DR: It is suggested that both FSH and LH play an important role in regulating circadian clock in the ovary; however, they might exert differential actions on the clockwork in vivo due to each specific role within ovarian physiology.

TL;DR: The results strongly suggest that deficiency of GDF-8 delays cell differentiation and causes great alterations in the cellular morphology of chicken embryonic myotubes.