M
Maria L. Dufau
Researcher at National Institutes of Health
Publications - 278
Citations - 12400
Maria L. Dufau is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Receptor & Gonadotropin. The author has an hindex of 68, co-authored 273 publications receiving 12151 citations. Previous affiliations of Maria L. Dufau include University of Manitoba & Sapienza University of Rome.
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Adrenocorticotropin action in isolated adrenal cells. The intermediate role of cyclic AMP in stimulation of corticosterone synthesis.
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Hormonal regulation of testicular luteinizing hormone receptors. Effects on cyclic AMP and testosterone responses in isolated Leydig cells.
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Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis
TL;DR: It is demonstrated that GRTH is essential for completion of spermatogenesis, insights into intrinsic requirements for spermiogenesis are provided, and a model for studies of male infertility and contraception is established.
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Structural organization of the rat luteinizing hormone (LH) receptor gene.
TL;DR: The luteinizing hormone (LH)/human chorionic gonadotropin (hCG) receptor gene was isolated from rat liver genomic libraries and spanned at least 75 kilobase pairs from nucleotide -2057 of the 5'-flanking region to the 3'-noncoding end, indicating the presence of multiple transcriptional initiation sites.
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Cellular Localization of Rat Testicular Aromatase Activity during Development
TL;DR: Leydig cells are the major site of estrogen synthesis in adult rat testis and the low aromatase activity observed in immature rat Leydig cells could partially explain the differential response of the mature and immatureRat testis to hCG-induced desensitization.