M
Masaharu Kaibe
Researcher at Osaka University
Publications - 9
Citations - 1084
Masaharu Kaibe is an academic researcher from Osaka University. The author has contributed to research in topics: Arterial stiffness & Pulse wave velocity. The author has an hindex of 7, co-authored 9 publications receiving 1029 citations.
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Journal ArticleDOI
Association of Hypoadiponectinemia With Impaired Vasoreactivity
Noriyuki Ouchi,Mitsuru Ohishi,Shinji Kihara,Tohru Funahashi,Tadashi Nakamura,Hiroyuki Nagaretani,Masahiro Kumada,Koji Ohashi,Yoshihisa Okamoto,Hitoshi Nishizawa,Ken Kishida,Norikazu Maeda,Azumi Nagasawa,Hideki Kobayashi,Hisatoyo Hiraoka,Norio Komai,Masaharu Kaibe,Hiromi Rakugi,Toshio Ogihara,Yuji Matsuzawa +19 more
TL;DR: Observations suggest that hypoadiponectinemia is associated with impaired endothelium-dependent vasorelaxation and that the measurement of plasma adiponectin level might be helpful as a marker of endothelial dysfunction.
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Deletion of Angiotensin-Converting Enzyme 2 Accelerates Pressure Overload-Induced Cardiac Dysfunction by Increasing Local Angiotensin II
Koichi Yamamoto,Mitsuru Ohishi,Tomohiro Katsuya,Norihisa Ito,Masashi Ikushima,Masaharu Kaibe,Yuji Tatara,Atsushi Shiota,Sumio Sugano,Satoshi Takeda,Hiromi Rakugi,Toshio Ogihara +11 more
TL;DR: Cardiac angiotensin II concentration and activity of mitogen-activated protein (MAP) kinases were markedly increased in ACE2−/y mice in response to TAC, and administration of candesartan attenuated the hypertrophic response and suppressed the activation of MAP kinases in ACE1−/Y mice.
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Comparison of arterial functional evaluations as a predictor of cardiovascular events in hypertensive patients: the Non-Invasive Atherosclerotic Evaluation in Hypertension (NOAH) study.
Minako Terai,Mitsuru Ohishi,Norihisa Ito,Takashi Takagi,Yuji Tatara,Masaharu Kaibe,Norio Komai,Hiromi Rakugi,Toshio Ogihara +8 more
TL;DR: Increased aortic stiffness evaluated by PWV is more prognostic of cardiovascular events in hypertensive patients than several non-invasive atherosclerotic evaluations.
Journal ArticleDOI
Serum interleukin-15 concentration in patients with essential hypertension.
Masaharu Kaibe,Mitsuru Ohishi,Norihisa Ito,Ming Yuan,Takashi Takagi,Minako Terai,Yuji Tatara,Norio Komai,Hiromi Rakugi,Toshio Ogihara +9 more
TL;DR: Clinical investigations suggest that a systemic inflammatory response involving IL-15 might be involved in the occurrence of cardiovascular disease in patients with essential hypertension.
Journal ArticleDOI
Serum hepatocyte growth factor concentration is correlated with the forearm vasodilator response in hypertensive patients.
Norio Komai,Mitsuru Ohishi,Ryuichi Morishita,Atsushi Moriguchi,Masaharu Kaibe,Keiko Matsumoto,Hiromi Rakugi,Jitsuo Higaki,Toshio Ogihara +8 more
TL;DR: Results suggest that in evaluation of serum HGF concentration, the forearm vasodilator response to reactive hyperemia and PWV might be useful for managing hypertension in patients who are receiving antihypertensive therapy.