Masahito Hagio

TL;DR: Cholic acid regulates the composition of gut microbiota in rats, inducing similar changes to those induced by high-fat diets, and these findings improve the understanding of the relationship between metabolic diseases andThe composition of the gastrointestinal microbiota.

TL;DR: The rationale for this hypothesis is discussed by evaluating reported diet-induced gut microbiota alterations based on the postulate that bile acids worked as an underlying determinant of the gut microbiota in response to a high-fat diet.

TL;DR: The method for analyzing BA composition in various tissues and intestinal contents using ultra performance liquid chromatography/electrospray ionization mass spectrometry (UPLC/ESI-MS) established will be useful for investigating the roles of BA metabolism under physiological and pathological conditions.

TL;DR: Using nestin to more accurately evaluate microvessel density in cancer specimens may be a novel prognostic indicator and nestin-targeted therapy may suppress tumor proliferation via inhibition of angiogenesis in numerous malignancies, including pancreatic cancer.

TL;DR: Results show that these two marine carotenoids inhibit lipase activity in the gastrointestinal lumen and suppress triglyceride absorption, and fucoxanthin was converted to fu Coxanthinol in the intestine and released into the lymph.