Satoshi Ishizuka

TL;DR: Cholic acid regulates the composition of gut microbiota in rats, inducing similar changes to those induced by high-fat diets, and these findings improve the understanding of the relationship between metabolic diseases andThe composition of the gastrointestinal microbiota.

TL;DR: The rationale for this hypothesis is discussed by evaluating reported diet-induced gut microbiota alterations based on the postulate that bile acids worked as an underlying determinant of the gut microbiota in response to a high-fat diet.

TL;DR: The method for analyzing BA composition in various tissues and intestinal contents using ultra performance liquid chromatography/electrospray ionization mass spectrometry (UPLC/ESI-MS) established will be useful for investigating the roles of BA metabolism under physiological and pathological conditions.

TL;DR: The findings suggest that the usual intake of polyphenols is relatively safe, but that a high intake by supplementation or by dietary habit of tannin affects only the Fe level.

TL;DR: Principal-component analysis of T-RFLP results revealed significant alterations in the bacterial populations of rats in the RAF and RCB groups; the population in the CB group was similar to that in the control group (group BD).