M
Masashi Miyano
Researcher at Aoyama Gakuin University
Publications - 15
Citations - 5477
Masashi Miyano is an academic researcher from Aoyama Gakuin University. The author has contributed to research in topics: G protein-coupled receptor & Thermus thermophilus. The author has an hindex of 5, co-authored 15 publications receiving 5322 citations.
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Journal ArticleDOI
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
Krzysztof Palczewski,Takashi Kumasaka,Tetsuya Hori,Craig A. Behnke,H. Motoshima,Brian A. Fox,I. Le Trong,David C. Teller,Tetsuji Okada,Ronald E. Stenkamp,Masaki Yamamoto,Masashi Miyano +11 more
TL;DR: This article determined the structure of rhodopsin from diffraction data extending to 2.8 angstroms resolution and found that the highly organized structure in the extracellular region, including a conserved disulfide bridge, forms a basis for the arrangement of the sevenhelix transmembrane motif.
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Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1.
Tetsuya Hori,Toshiaki Okuno,Kunio Hirata,Keitaro Yamashita,Yoshiaki Kawano,Masaki Yamamoto,Masakatsu Hato,Motonao Nakamura,Motonao Nakamura,Takao Shimizu,Takehiko Yokomizo,Masashi Miyano,Shigeyuki Yokoyama +12 more
TL;DR: The crystal structure of the leukotriene B4 (LTB4) receptor BLT1 bound with BIIL260 is determined, and the unprecedented inverse-agonist mechanism by the benzamidine moiety will enable the rational development of inverse agonists specific for each GPCR.
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Crystallization and preliminary crystallographic analysis of the human calcineurin homologous protein CHP2 bound to the cytoplasmic region of the Na+/H+ exchanger NHE1.
Youssef Ben Ammar,Soichi Takeda,Mitsuaki Sugawara,Masashi Miyano,Hidezo Mori,Shigeo Wakabayashi +5 more
TL;DR: The complex CHP2-NHE1 (amino acids 503-545) has been crystallized by the sitting-drop vapour-diffusion method using PEG 3350 as precipitant to understand the regulatory mechanism of NHE1 byCHP2.
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The catalytic architecture of leukotriene C4 synthase with two arginine residues
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Seleno-detergent MAD phasing of leukotriene C4 synthase in complex with dodecyl-β-D-selenomaltoside.
TL;DR: Dodecyl-β-d-selenomaltoside in a leukotriene C4 synthase crystal exhibited sufficient anomalous diffraction for multiwavelength anomalousdiffraction phasing.