M
Masashi Takeda
Publications - 34
Citations - 4541
Masashi Takeda is an academic researcher. The author has contributed to research in topics: Carcinoma & Lung cancer. The author has an hindex of 8, co-authored 34 publications receiving 4344 citations.
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Journal ArticleDOI
Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.
Seiichi Hirota,Koji Isozaki,Yasuhiro Moriyama,Koji Hashimoto,Toshirou Nishida,Shingo Ishiguro,Kiyoshi Kawano,Masato Hanada,Akihiko Kurata,Masashi Takeda,Ghulam Muhammad Tunio,Yuji Matsuzawa,Yuzuru Kanakura,Yasuhisa Shinomura,Yukihiko Kitamura +14 more
TL;DR: Sequencing of c-kit complementary DNA from five GISTs revealed mutations in the region between the transmembrane and tyrosine kinase domains, suggesting that the mutations contribute to tumor development.
Journal Article
Primary signet-ring cell carcinoma of the colon and rectum: report of eight cases and review of 154 Japanese cases.
Tomoki Makino,Toshimasa Tsujinaka,Hideyuki Mishima,Masakazu Ikenaga,Toshiro Sawamura,Shoji Nakamori,Kazumasa Fujitani,Motohiro Hirao,Masaki Kashiwazaki,Norikazu Masuda,Masashi Takeda,Masayuki Mano +11 more
TL;DR: Since the prognosis of primary signet-ring cell colorectal carcinoma is extremely poor, early diagnosis and aggressive treatment strategy are necessary.
Journal ArticleDOI
Impact of biomarker changes during neoadjuvant chemotherapy for clinical response in patients with residual breast cancers.
Yukie Enomoto,Takashi Morimoto,Arisa Nishimukai,Tomoko Higuchi,Ayako Yanai,Yoshimasa Miyagawa,Keiko Murase,Michiko Imamura,Yuichi Takatsuka,Takashi Nomura,Masashi Takeda,Takahiro Watanabe,Seiichi Hirota,Yasuo Miyoshi +13 more
TL;DR: The impact of Ki67 suppression on clinical response seems to be restricted to ER-positive breast cancers, and inhibition of estrogen signaling due to chemotherapy-induced amenorrhea may be involved in this association.
Journal ArticleDOI
An icteric type hepatocellular carcinoma with no detectable tumor in the liver: report of a case.
Tomoki Makino,Shoji Nakamori,Masaki Kashiwazaki,Norikazu Masuda,Masakazu Ikenaga,Motohiro Hirao,Kazumasa Fujitani,Hideyuki Mishima,Toshiro Sawamura,Masashi Takeda,Masayuki Mano,Toshimasa Tsujinaka +11 more
TL;DR: An intraoperative histological examination of the tumor showed a well-differentiated hepatocellular carcinoma, and no lesions were detected in the liver by ultrasonography, palpation during the operation, or a computed tomography scan after the operation.
Journal ArticleDOI
Surgical resection of advanced non-small cell lung cancer after a response to EGFR-TKI: presentation of two cases and a literature review.
TL;DR: Two patients who underwent residual tumor resection after responding to EGFR-TKIs for advanced non-small cell lung cancer (NSCLC) harboring EGFR gene mutations are described along with a review of the literature.