Masato Nakaguro

TL;DR: Wang et al. as mentioned in this paper proposed a method for cancer subtype classification from histopathological images, which can automatically detect tumor-specific features in a given whole slide image (WSI), i.e., a large-sized image (typically 40,000x40,000 pixels) of an entire pathological tissue slide, which consists of cancer and non-cancer portions.

TL;DR: A new CNN-based cancer subtype classification method is developed by effectively combining multiple-instance, domain adversarial, and multi-scale learning frameworks in order to overcome practical difficulties.

TL;DR: The findings establish the critical role of the neuronal differentiation factor NeuroD1 in neuroblastoma as well as its functional relationship with the neuronal repellent factor Slit2 and the functions identified for NeuroD 1 in cell motility and tumor sphere growth.

TL;DR: This case showed that even if at a late phase, long-term use of immune checkpoint inhibitors might to lead immune-related adverse events including myocarditis, and nivolumab therapy rarely occurred at > 2 months use in clinical trials.

TL;DR: Several clinical studies have shown promising results using targeted therapy for androgen receptor (AR) and human epidermal growth factor receptor 2 (HER2), and the latest version of the National Comprehensive Cancer Network guidelines recommends the evaluation of AR and HER2 status before treatment.