M
Masayuki Saito
Researcher at Hokkaido University
Publications - 244
Citations - 12897
Masayuki Saito is an academic researcher from Hokkaido University. The author has contributed to research in topics: Brown adipose tissue & Adipose tissue. The author has an hindex of 54, co-authored 241 publications receiving 11541 citations. Previous affiliations of Masayuki Saito include University of Liège & Toshiba.
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Journal ArticleDOI
High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity
Masayuki Saito,Yuko Okamatsu-Ogura,Mami Matsushita,Kumiko Watanabe,Takeshi Yoneshiro,Junko Nio-Kobayashi,Toshihiko Iwanaga,Masao Miyagawa,Toshimitsu Kameya,Kunihiro Nakada,Yuko Kawai,Masayuki Tsujisaki +11 more
TL;DR: The findings, being against the conventional view, indicate the high incidence of metabolically active BAT in adult humans and suggest a role in the control of body temperature and adiposity.
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Recruited brown adipose tissue as an antiobesity agent in humans
Takeshi Yoneshiro,Sayuri Aita,Mami Matsushita,Takashi Kayahara,Toshimitsu Kameya,Yuko Kawai,Toshihiko Iwanaga,Masayuki Saito +7 more
TL;DR: Examination of the effects of repeated stimulation by cold and capsinoids in healthy human subjects with low BAT activity demonstrates that human BAT can be recruited even in individuals with decreased BAT activity, thereby contributing to body fat reduction.
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Age-related decrease in cold-activated brown adipose tissue and accumulation of body fat in healthy humans.
Takeshi Yoneshiro,Sayuri Aita,Mami Matsushita,Yuko Okamatsu-Ogura,Toshimitsu Kameya,Yuko Kawai,Masao Miyagawa,Masayuki Tsujisaki,Masayuki Saito +8 more
TL;DR: The results suggest that decreased BAT activity may be associated with accumulation of body fat with age, and the adiposity‐related parameters showed some sex differences, but increased with age in the BAT‐negative group, in both sexes.
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Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men.
Takeshi Yoneshiro,Sayuri Aita,Mami Matsushita,Toshimitsu Kameya,Kunihiro Nakada,Yuko Kawai,Masayuki Saito +6 more
TL;DR: The results suggest that BAT is involved in cold‐induced increases in whole‐body energy expenditure, and, thereby, the control of body temperature and adiposity in adult humans.
Journal ArticleDOI
FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets
Naonobu Nishino,Yoshikazu Tamori,Sanshiro Tateya,Takayuki Kawaguchi,Tetsuro Shibakusa,Wataru Mizunoya,Kazuo Inoue,Riko Kitazawa,Sohei Kitazawa,Yasushi Matsuki,Ryuji Hiramatsu,Satoru Masubuchi,Asako Omachi,Kazuhiro Kimura,Masayuki Saito,Taku Amo,Shigeo Ohta,Tomohiro Yamaguchi,Takashi Osumi,Jinglei Cheng,Toyoshi Fujimoto,Harumi Nakao,Kazuki Nakao,Atsu Aiba,Hitoshi Okamura,Tohru Fushiki,Masato Kasuga +26 more
TL;DR: The results suggest that FSP27 contributes to efficient energy storage in WAT by promoting the formation of unilocular lipid droplets, thereby restricting lipolysis and finding that the nature of lipid accumulation in Wat appears to be associated with maintenance of energy balance and insulin sensitivity.