M
Mathue Baker
Researcher at New York Medical College
Publications - 3
Citations - 4383
Mathue Baker is an academic researcher from New York Medical College. The author has contributed to research in topics: Hepatocyte growth factor & Stem cell. The author has an hindex of 3, co-authored 3 publications receiving 4284 citations. Previous affiliations of Mathue Baker include Harvard University.
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Journal ArticleDOI
Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration
Antonio Paolo Beltrami,Laura Barlucchi,Daniele Torella,Mathue Baker,Federica Limana,Stefano Chimenti,Hideko Kasahara,Marcello Rota,Ezio Musso,Konrad Urbanek,Annarosa Leri,Jan Kajstura,Bernardo Nadal-Ginard,Piero Anversa +13 more
TL;DR: The existence of Lin(-) c-kit(POS) cells with the properties of cardiac stem cells, which are self-renewing, clonogenic, and multipotent, giving rise to myocytes, smooth muscle, and endothelial cells are reported.
Journal ArticleDOI
Cardiac Stem Cells Possess Growth Factor-Receptor Systems That After Activation Regenerate the Infarcted Myocardium, Improving Ventricular Function and Long-Term Survival
Konrad Urbanek,Marcello Rota,Stefano Cascapera,Claudia Bearzi,Angelo Nascimbene,Antonella De Angelis,Toru Hosoda,Stefano Chimenti,Mathue Baker,Federica Limana,Daria Nurzynska,Daniele Torella,Francesco Rotatori,Raffaella Rastaldo,Ezio Musso,Federico Quaini,Annarosa Leri,Jan Kajstura,Piero Anversa +18 more
TL;DR: The heart has an endogenous reserve of CSCs-ECCs that can be activated to reconstitute dead myocardium and recover cardiac function and induced increased survival and rescued animals with infarcts that were up to 86% of the ventricle, which are commonly fatal.
Journal ArticleDOI
Activation of Cardiac Progenitor Cells Reverses the Failing Heart Senescent Phenotype and Prolongs Lifespan
Arantxa Gonzalez,Marcello Rota,Daria Nurzynska,Yu Misao,Jochen Tillmanns,Caroline Ojaimi,M. Elena Padin-Iruegas,Patrick Müller,Grazia Esposito,Claudia Bearzi,Serena Vitale,Buddhadeb Dawn,Santosh K. Sanganalmath,Mathue Baker,Thomas H. Hintze,Roberto Bolli,Konrad Urbanek,Toru Hosoda,Piero Anversa,Jan Kajstura,Annarosa Leri +20 more
TL;DR: It is identified that chronological age leads to telomeric shortening in CPCs, which by necessity generate a differentiated progeny that rapidly acquires the senescent phenotype conditioning organ aging.