M
Matthew Jessulat
Researcher at University of Regina
Publications - 35
Citations - 998
Matthew Jessulat is an academic researcher from University of Regina. The author has contributed to research in topics: Saccharomyces cerevisiae & Protein–protein interaction. The author has an hindex of 18, co-authored 33 publications receiving 871 citations. Previous affiliations of Matthew Jessulat include University of Ottawa & Carleton University.
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Journal ArticleDOI
PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs
Sylvain Pitre,Frank Dehne,Albert Chan,James J. Cheetham,Alex Duong,Andrew Emili,Marinella Gebbia,Jack Greenblatt,Matthew Jessulat,Nevan J. Krogan,Xuemei Luo,Ashkan Golshani +11 more
TL;DR: A novel Protein-Protein Interaction Prediction Engine capable of predicting protein-protein interactions for any target pair of the yeast Saccharomyces cerevisiae proteins from their primary structure and without the need for any additional information or predictions about the proteins is explained.
Journal ArticleDOI
Mapping the functional yeast ABC transporter interactome
Jamie Snider,Asad Hanif,Mid Eum Lee,Ke Jin,Analyn Yu,Chris Graham,Chris Graham,Matthew Chuk,Dunja Damjanovic,Marta Wierzbicka,Priscilla Tang,Dina A. Balderes,Victoria Wong,Matthew Jessulat,Katelyn D. Darowski,Bryan Joseph San Luis,Igor Shevelev,Stephen L. Sturley,Charles Boone,Jack Greenblatt,Zhaolei Zhang,Christian M. Paumi,Mohan Babu,Hay-Oak Park,Susan Michaelis,Igor Stagljar +25 more
TL;DR: It is shown that ABC transporters physically associate with proteins involved in a surprisingly diverse range of functions, and the importance of the physical interactions of ABCtransporters in both the regulation of one another and in the modulation of proteinsinvolved in zinc homeostasis is examined.
Journal ArticleDOI
Global investigation of protein–protein interactions in yeast Saccharomyces cerevisiae using re-occurring short polypeptide sequences
Sylvain Pitre,C. North,M. Alamgir,Matthew Jessulat,Albert Chan,X. Luo,James R. Green,Michel Dumontier,Frank Dehne,Ashkan Golshani +9 more
TL;DR: This work reports the first all-to-all sequence-based computational screen of PPIs in yeast, Saccharomyces cerevisiae in which it identifies 29 589 high confidence interactions of ∼2 × 107 possible pairs, of which 14 438 PPIs have not been previously reported and may represent novel interactions.
Journal ArticleDOI
Colony size measurement of the yeast gene deletion strains for functional genomics.
Negar Memarian,Negar Memarian,Matthew Jessulat,Javad Alirezaie,Javad Alirezaie,Nadereh Mir-Rashed,Jianhua Xu,Mehri Zareie,Myron L. Smith,Ashkan Golshani +9 more
TL;DR: A computerized image analysis system called Growth Detector, to automatically acquire quantitative and comparative information for yeast colony growth, which successfully detected a genetic linkage between the molecular activity of the plant-derived antifungal compound berberine and gene expression components, among other cellular processes.
Journal ArticleDOI
Short Co-occurring Polypeptide Regions Can Predict Global Protein Interaction Maps
Sylvain Pitre,Mohsen Hooshyar,Andrew Schoenrock,Bahram Samanfar,Matthew Jessulat,James R. Green,Frank Dehne,Ashkan Golshani +7 more
TL;DR: It is shown that the presence of co-occurring short polypeptide sequences between interacting protein partners appears to be conserved across different organisms and that global PPIs can be predicted from previously reported PPIs within the same or a different organism using protein primary sequences.