M
Matthew Jones
Researcher at Manchester Academic Health Science Centre
Publications - 67
Citations - 4810
Matthew Jones is an academic researcher from Manchester Academic Health Science Centre. The author has contributed to research in topics: Frontotemporal dementia & Integrin. The author has an hindex of 29, co-authored 66 publications receiving 3898 citations. Previous affiliations of Matthew Jones include State University of New York Upstate Medical University & Wellcome Trust Centre for Cell-Matrix Research.
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Journal ArticleDOI
Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations
Julie S. Snowden,Sara Rollinson,Jennifer C. Thompson,Jennifer C. Thompson,Jennifer M. Harris,Jennifer M. Harris,Cheryl L. Stopford,Cheryl L. Stopford,Anna Richardson,Anna Richardson,Matthew Jones,Matthew Jones,Alexander Gerhard,Alexander Gerhard,Yvonne S Davidson,Andrew C Robinson,Linda Gibbons,Quan Hu,Daniel DuPlessis,David Neary,David Neary,David M. A. Mann,Stuart Pickering-Brown +22 more
TL;DR: Mutations in the C9ORF72 gene may be a major cause not only of frontotemporal dementia with motor neuron disease but also of late onset psychosis, and the behavioural characteristics of patients with C9 ORF72 mutations are qualitatively distinct.
Journal ArticleDOI
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors
Andrew R. Reynolds,Andrew R. Reynolds,Ian R. Hart,Alan R. Watson,Jonathan Welti,Rita Silva,Stephen D. Robinson,Georges Da Violante,Morgane Gourlaouen,Mishal Salih,Matthew Jones,Dylan T. Jones,Garry Saunders,Vassiliki Kostourou,Françoise Perron-Sierra,Jim C. Norman,Gordon C. Tucker,Kairbaan Hodivala-Dilke +17 more
TL;DR: It is shown that low concentrations of these inhibitors promote VEGF-mediated angiogenesis by altering αvβ3 integrin and vascular endothelial growth factor receptor-2 trafficking, thereby promoting endothelial cell migration to V EGF.
Journal ArticleDOI
Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology
John T. O'Brien,Clive Holmes,Matthew Jones,Roy W. Jones,Gill Livingston,Ian G. McKeith,Peter Mittler,Peter Passmore,Craig W. Ritchie,Louise Robinson,Elizabeth L Sampson,John-Paul Taylor,Alan J. Thomas,Alistair Burns +13 more
TL;DR: The British Association for Psychopharmacology coordinated a meeting of experts to review and revise its previous 2011 guidelines for clinical practice with anti-dementia drugs, with the consensus statement focusing on medication.
Journal ArticleDOI
Endocytic recycling pathways : emerging regulators of cell migration
TL;DR: Detailed descriptions have emerged of the mechanisms that recruit integrins and growth factor receptors to Rab4- and Rab11-driven pathways in cell migration within a variety of physiological contexts.