Matthias Kumpf

TL;DR: This publication is a comprehensive, interdisciplinary, evidence and consensus-based set of level 3 guidelines for intensive care medicine, designed for all ICU professionals, and takes into account all critically ill patient populations.

TL;DR: It is found that dornase alfa was beneficial and safe, and possibly of value from the first day of mechanical ventilation onward, particularly when longer ventilation is expected in fluid‐restricted children after cardiac surgery.

TL;DR: There is still little evidence of clinical use of analgesia and sedation protocols and the impact on withdrawal symptoms in critically ill children, and several guidelines and protocols are developed and implemented for adults.

TL;DR: Bronchoscopy was helpful in the description of the severity and length of bronchial stenoses, but it was not possible to establish a diagnosis of BB based on this method in two patients, since it was difficult or even impossible to differentiate the bifurcation from the pseudocarina.

TL;DR: Intratracheal instillation of rhDNase is an effective adjunct to conservative therapy of atelectases in children and further randomized controlled prospective studies are necessary.