M
Maty Tzukerman
Researcher at Technion – Israel Institute of Technology
Publications - 38
Citations - 2385
Maty Tzukerman is an academic researcher from Technion – Israel Institute of Technology. The author has contributed to research in topics: Embryonic stem cell & Stem cell. The author has an hindex of 18, co-authored 37 publications receiving 2299 citations. Previous affiliations of Maty Tzukerman include Rappaport Faculty of Medicine & Rambam Health Care Campus.
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Journal ArticleDOI
Insulin production by human embryonic stem cells.
TL;DR: Sp spontaneous in vitro differentiation that included the generation of cells with characteristics of insulin-producing beta-cells is observed, validating the hES cell model system as a potential basis for enrichment of human beta- cells or their precursors, as a possible future source for cell replacement therapy in diabetes.
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Multipotent Vasculogenic Pericytes From Human Pluripotent Stem Cells Promote Recovery of Murine Ischemic Limb
Ayelet Dar,Hagit Domev,Oren Ben-Yosef,Maty Tzukerman,Naama Zeevi-Levin,Atara Novak,Igal Germanguz,Michal Amit,Joseph Itskovitz-Eldor +8 more
TL;DR: Derivation of vasculogenic and multipotent pericytes from hPSC can be used for the development of vasculusogenic models using multiple vasculogenesis cell types for basic research and drug screening and can contribute to angiogenic regenerative medicine.
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Kidney-specific Overexpression of Sirt1 Protects against Acute Kidney Injury by Retaining Peroxisome Function
Kazuhiro Hasegawa,Shu Wakino,Kyoko Yoshioka,Satoru Tatematsu,Yoshikazu Hara,Hitoshi Minakuchi,Keiko Sueyasu,Naoki Washida,Hirobumi Tokuyama,Maty Tzukerman,Karl Skorecki,Koichi Hayashi,Hiroshi Itoh +12 more
TL;DR: Results indicate that Sirt1 overexpression in proximal tubules rescues cisplatin-induced AKI by maintaining peroxisomes number and function, concomitant up-regulation of catalase, and elimination of renal ROS levels.
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p53-dependent down-regulation of telomerase is mediated by p21waf1.
Igor Shats,Michael Milyavsky,Xiaohu Tang,Perry Stambolsky,Neta Erez,Ran Brosh,Ira Kogan,Ilana Braunstein,Maty Tzukerman,Doron Ginsberg,Varda Rotter +10 more
TL;DR: The results suggest that repression of hTERT by endogenous p53 is mediated by p21 and E2F, and this study re-evaluated the role of p53 in telomerase regulation using isogenic cell lines expressing physiological levels of p 53.
Journal Article
Isolation and Characterization of Human Recombinant Antibodies Endowed with the Antigen-specific, Major Histocompatibility Complex-restricted Specificity of T Cells Directed toward the Widely Expressed Tumor T-cell Epitopes of the Telomerase Catalytic Subunit
Avital Lev,Galit Denkberg,Cyril J. Cohen,Maty Tzukerman,Karl Skorecki,Patrick Chames,Hennie R. Hoogenboom,Yoram Reiter +7 more
TL;DR: These findings demonstrate for the first time the ability to transform the unique fine specificity but low intrinsic affinity of TCRs on T cells into high-affinity soluble antibody molecules endowed with a T-cell antigen receptor-like specificity.