M
Mauro Corsi
Researcher at GlaxoSmithKline
Publications - 93
Citations - 3703
Mauro Corsi is an academic researcher from GlaxoSmithKline. The author has contributed to research in topics: Receptor & Agonist. The author has an hindex of 31, co-authored 90 publications receiving 3466 citations. Previous affiliations of Mauro Corsi include University of Verona.
Papers
More filters
Journal ArticleDOI
Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice.
Christian Chiamulera,Mark P. Epping-Jordan,Alessandro Zocchi,Clara Marcon,Cécilia Cottiny,Stefano Tacconi,Mauro Corsi,Francesco Orzi,François Conquet +8 more
TL;DR: It is shown that mice lacking the mGluR5 gene do not self-administer cocaine, and show no increased locomotor activity following cocaine treatment, despite showing cocaine-induced increases in nucleus accumbens (NAcc) dopamine (DA) levels similar to wild-type mice.
Journal ArticleDOI
Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain.
Laura Caberlotto,Yasmin L. Hurd,Paul R. Murdock,Jean Philippe Wahlin,Sergio Melotto,Mauro Corsi,Renzo Carletti +6 more
TL;DR: The anatomical evidence that the NK1 receptors have a strong association with neuronal systems relevant to mood regulation and stress in the human brain is provided, but do not suggest a region‐specific role of the two isoforms in the CNS.
Journal ArticleDOI
The Use of Knock-Out Mice Unravels Distinct Roles for mGlu2 and mGlu3 Metabotropic Glutamate Receptors in Mechanisms of Neurodegeneration/Neuroprotection
Corrado Corti,Giuseppe Battaglia,Gemma Molinaro,Barbara Riozzi,Anna Pittaluga,Mauro Corsi,Manolo Mugnaini,Ferdinando Nicoletti,Valeria Bruno +8 more
TL;DR: It is concluded that neuroprotection bymGlu2/3 receptor agonists requires the activation of astrocytic mGlu3 receptors, whereas, unexpectedly, activation of mGLU2 receptors might be harmful to neurons exposed to toxic insults.
Journal ArticleDOI
The Ca(V)3.3 calcium channel is the major sleep spindle pacemaker in thalamus.
Simone Astori,Ralf D. Wimmer,Haydn M. Prosser,Haydn M. Prosser,Corrado Corti,Mauro Corsi,Nicolas Liaudet,Andrea Volterra,Paul Franken,John P. Adelman,Anita Lüthi +10 more
TL;DR: A central role is identified for CaV3.3 channels in the rhythmogenic properties of the sleep-spindle generator and a molecular target is provided to elucidate the roles of sleep spindles for brain function and development.
Journal ArticleDOI
Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors.
TL;DR: Findings raise the possibility of a MAPK cascade involvement in glutamate‐dependent neuronal plasticity mediated through stimulation of mGluRs in the control of cellular responses to changes in the external environment.