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Andrea Volterra
Researcher at University of Lausanne
Publications - 106
Citations - 17081
Andrea Volterra is an academic researcher from University of Lausanne. The author has contributed to research in topics: Glutamate receptor & Astrocyte. The author has an hindex of 50, co-authored 105 publications receiving 15050 citations. Previous affiliations of Andrea Volterra include Columbia University & University of Milan.
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Journal ArticleDOI
Astrocytes, from brain glue to communication elements: the revolution continues.
Andrea Volterra,Jacopo Meldolesi +1 more
TL;DR: The recent recognition that astrocytes are organized in separate territories and possess active properties — notably a competence for the regulated release of 'gliotransmitters', including glutamate — has enabled us to develop an understanding of previously unknown functions for astroCytes.
Journal ArticleDOI
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes.
Paola Bezzi,Giorgio Carmignoto,Lucia Pasti,Sabino Vesce,Daniela Rossi,Barbara Lodi Rizzini,Tullio Pozzan,Andrea Volterra +7 more
TL;DR: It is shown that coactivation of the AMPA/kainate and metabotropic glutamate receptors (mGluRs) on astrocytes stimulates these cells to release glutamate through a Ca2+-dependent process mediated by prostaglandins, revealing a new pathway of regulated transmitter release from astroCytes and outlining the existence of an integrated glutamatergic cross-talk between neurons and astroicytes in situ.
Journal ArticleDOI
CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity.
Paola Bezzi,Maria Domercq,Liliana Brambilla,Rossella Galli,Dominique Schols,Erik De Clercq,Angelo L. Vescovi,Giacinto Bagetta,George Kollias,Jacopo Meldolesi,Andrea Volterra +10 more
TL;DR: It is demonstrated that altered glial communication has direct neuropathological consequences and that agents interfering with CXCR4-dependent astrocyte–microglia signaling prevent neuronal apoptosis induced by the HIV-1 coat glycoprotein, gp120IIIB.
Journal ArticleDOI
Gliotransmitters Travel in Time and Space
Alfonso Araque,Giorgio Carmignoto,Philip G. Haydon,Stéphane H. R. Oliet,Richard Robitaille,Andrea Volterra +5 more
TL;DR: It is proposed that astrocytes mainly signal through high-affinity slowly desensitizing receptors to modulate neurons and perform integration in spatiotemporal domains complementary to those of neurons.
Journal ArticleDOI
Reactive astrocyte nomenclature, definitions, and future directions
Carole Escartin,Elena Galea,Andras Lakatos,James P. O'Callaghan,Gabor C. Petzold,Gabor C. Petzold,Alberto Serrano-Pozo,Christian Steinhäuser,Andrea Volterra,Giorgio Carmignoto,Giorgio Carmignoto,Amit Agarwal,Nicola J. Allen,Alfonso Araque,Luis Barbeito,Ari Barzilai,Dwight E. Bergles,Gilles Bonvento,Arthur M. Butt,Wei Ting Chen,Martine Cohen-Salmon,Colm Cunningham,Benjamin Deneen,Bart De Strooper,Bart De Strooper,Blanca Diaz-Castro,Cinthia Farina,Marc R. Freeman,Vittorio Gallo,James E. Goldman,Steven A. Goldman,Steven A. Goldman,Magdalena Götz,Antonia Gutierrez,Philip G. Haydon,Dieter Henrik Heiland,Elly M. Hol,Matthew Holt,Masamitsu Iino,Ksenia V. Kastanenka,Helmut Kettenmann,Baljit S. Khakh,Schuichi Koizumi,C. Justin Lee,Shane A. Liddelow,Brian A. MacVicar,Pierre J. Magistretti,Pierre J. Magistretti,Albee Messing,Anusha Mishra,Anna V. Molofsky,Keith K. Murai,Christopher M. Norris,Seiji Okada,Stéphane H. R. Oliet,João Filipe Oliveira,João Filipe Oliveira,Aude Panatier,Vladimir Parpura,Marcela Pekna,Milos Pekny,Luc Pellerin,Gertrudis Perea,Beatriz G. Pérez-Nievas,Frank W. Pfrieger,Kira E. Poskanzer,Francisco J. Quintana,Richard M. Ransohoff,Miriam Riquelme-Perez,Stefanie Robel,Christine R. Rose,Jeffrey D. Rothstein,Nathalie Rouach,David H. Rowitch,Alexey Semyanov,Alexey Semyanov,Swetlana Sirko,Harald Sontheimer,Raymond A. Swanson,Javier Vitorica,Ina B. Wanner,Levi B. Wood,Jia Qian Wu,Binhai Zheng,Eduardo R. Zimmer,Robert Zorec,Michael V. Sofroniew,Alexei Verkhratsky,Alexei Verkhratsky +88 more
TL;DR: In this article, the authors point out the shortcomings of binary divisions of reactive astrocytes into good-vs-bad, neurotoxic vs-neuroprotective or A1-vs.A2.