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Mauro Schneider Oliveira

Researcher at Universidade Federal de Santa Maria

Publications -  113
Citations -  2527

Mauro Schneider Oliveira is an academic researcher from Universidade Federal de Santa Maria. The author has contributed to research in topics: Epilepsy & Oxidative stress. The author has an hindex of 28, co-authored 106 publications receiving 2078 citations. Previous affiliations of Mauro Schneider Oliveira include Universidade Federal do Pampa & Universidade Federal do Rio Grande do Sul.

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Cyclooxygenase-2/PGE2 pathway facilitates pentylenetetrazol-induced seizures

TL;DR: Strong converging pharmacological evidence is shown supporting a facilitatory role for the COX-2/PGE(2) pathway in the seizures induced by PTZ, and whether selective COx-2 inhibitors are safer anti-inflammatory drugs for epileptic patients than nonspecific inhibitors remains to be determined.
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GM1 ganglioside prevents seizures, Na+,K+-ATPase activity inhibition and oxidative stress induced by glutaric acid and pentylenetetrazole.

TL;DR: It is shown that GA inhibits Na+,K+-ATPase activity and increases oxidative damage markers (total protein carbonylation and thiobarbituric acid-reactive substances-TBARS) production in striatal homogenates from rats in vitro and ex vivo, and GM1 protects against GA-induced seizures and GABA(A) receptor-mediated mechanisms.
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Neuroprotective effect of physical exercise in a mouse model of Alzheimer's disease induced by β-amyloid₁₋₄₀ peptide.

TL;DR: It is suggested that exercise can prevent the cognitive decline, oxidative stress, and neuroinflammation induced by Aβ1–40 in mice supporting the hypothesis that Exercise can be used as a non-pharmacological tool to reduce the symptoms of AD.
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Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures

TL;DR: The present data suggest that β-caryophyllene displays anticonvulsant activity against seizures induced by PTZ in mice, and it is found that mice treated with an anticonVulsant dose of β- caryophyLLene displayed an improved recognition index in the object recognition test.