M
Max Ferretti
Researcher at University of Pennsylvania
Publications - 19
Citations - 609
Max Ferretti is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 9, co-authored 12 publications receiving 381 citations. Previous affiliations of Max Ferretti include Scripps Health & University of California, San Francisco.
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Journal ArticleDOI
Rps26 directs mRNA-specific translation by recognition of Kozak sequence elements.
Max Ferretti,Homa Ghalei,Ethan A Ward,Elizabeth L Potts,Elizabeth L Potts,Elizabeth L Potts,Katrin Karbstein +6 more
TL;DR: The production of specialized ribosomes, which play physiological roles in augmenting the well-characterized transcriptional stress response with a heretofore unknown translational response, thereby creating a feed-forward loop in gene expression is described, which can explain the pathogenesis of DBA.
Journal ArticleDOI
Pharmacological activation of STING blocks SARS-CoV-2 infection.
Minghua Li,Max Ferretti,Baoling Ying,Hélène Descamps,Emily M. Lee,Mark Dittmar,Jae Seung Lee,Kanupriya Whig,Brinda Kamalia,Lenka Dohnalová,Giulia T. Uhr,Hoda Zarkoob,Yu-Chi Chen,Holly Ramage,Marc Ferrer,Kristen W. Lynch,David C. Schultz,Christoph A. Thaiss,Michael S. Diamond,Sara Cherry +19 more
TL;DR: In this paper, the small molecule STING agonist diABZI was used to inhibit SARS-CoV-2 infection of diverse strains including variants of concern (B.1.351) by transiently stimulating interferon (IFN) signaling.
Journal ArticleDOI
Does functional specialization of ribosomes really exist
Max Ferretti,Katrin Karbstein +1 more
TL;DR: A set of important controls are suggested to validate functional diversification, defined as diverse ribosome populations differentially affecting translation of distinct mRNA (classes) based on observations and the commonly observed cellular responses to perturbations in the system.
Journal ArticleDOI
New Insights on the Morphology of Adult Mouse Penis
Esequiel Rodriguez,Dana A. Weiss,Jennifer H. Yang,Julia Menshenina,Max Ferretti,Tristan J. Cunha,Dale Barcellos,Lok Yun Chan,Gail P. Risbridger,Gerald R. Cunha,Laurence S. Baskin +10 more
TL;DR: Novel paired erectile bodies, the male urogenital mating protuberance (MUMP), and the urethral meatus are discovered and quantified by morphometric analysis to provide accurate morphological end points of sex differentiation of mouse penis.
Journal ArticleDOI
Specific morphogenetic events in mouse external genitalia sex differentiation are responsive/dependent upon androgens and/or estrogens
Esequiel Rodriguez,Dana A. Weiss,Max Ferretti,Hong Wang,Julia Menshenia,Gail P. Risbridger,David J. Handelsman,Gerald R. Cunha,Laurence S. Baskin +8 more
TL;DR: It is demonstrated that the presence or absence of androgen prenatally specifies penile versus clitoral identity and differentiated penile features emerge postnatally and are sensitive to and dependent upon prenatal or pre- and postnatal androgen.