M
May Azzawi
Researcher at Manchester Metropolitan University
Publications - 55
Citations - 3948
May Azzawi is an academic researcher from Manchester Metropolitan University. The author has contributed to research in topics: Eosinophil & Endothelium. The author has an hindex of 20, co-authored 53 publications receiving 3731 citations. Previous affiliations of May Azzawi include National Institutes of Health & Manchester Royal Infirmary.
Papers
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Journal ArticleDOI
Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma.
May Azzawi,B. Bradley,Peter K. Jeffery,Anthony J. Frew,Andrew J. Wardlaw,Knowles G,B. Assoufi,J.V. Collins,Stephen R. Durham,A. B. Kay +9 more
TL;DR: Examination of mucosal biopsies obtained from both central and subsegmental bronchi showed that the highest number of CD45-, DC3-, DC4-, and CD8-positive cells were found in the group with asthma, and there was a significant increase in the number of interleukin-2 receptor (CD25)-positive cells.
Journal ArticleDOI
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.
Qutayba Hamid,May Azzawi,Sun Ying,Redwan Moqbel,Andrew J. Wardlaw,Christopher Corrigan,B. Bradley,Stephen R. Durham,J.V. Collins,Peter K. Jeffery +9 more
TL;DR: Evidence is provided for the cellular localization of IL-5 mRNA in the bronchial mucosa of asthmatics and supports the concept that this cytokine regulates eosinophil function in Bronchial asthma.
Journal ArticleDOI
Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness.
B. Bradley,May Azzawi,Mikila R. Jacobson,B. Assoufi,J.V. Collins,A M Irani,L.B Schwartz,Stephen R. Durham,Peter K. Jeffery,A. B. Kay +9 more
TL;DR: The results support the hypothesis that activated (CD25) T-lymphocytes release products which regulate recruitment of EOSs into the airway wall, and suggest that asthma is not associated with hyperplasia of either mucosal-type or connective tissue-type mast cell.
Journal ArticleDOI
293 Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
A. B. Kay,O. Hamid,May Azzawi,Sun Ying,R. Mogbel,Andrew J. Wardlaw,Christopher Corrigan,B. Bradley,Stephen R. Durham,J.V. Collins,Peter K. Jeffery,Diana J. Quint +11 more
TL;DR: Evidence is provided for the cellular localization of IL-5 mRNA in the bronchial mucosa of asthmatics and supports the concept that this cytokine regulates eosinophil function in Bronchial asthma.
Journal ArticleDOI
T lymphocytes and activated eosinophils in airway mucosa in fatal asthma and cystic fibrosis
TL;DR: A role for the T lymphocyte in the pathogenesis of fatal asthma and CF is supported, and subjects with acute severe asthma who had had a duration of terminal illness exceeding, as compared with less than, 24 h are supported.