Meg J. Spriggs

TL;DR: For instance, this article found that positive expectancy scores at baseline predicted subsequent improvements in well-being, suggestive of a significant placebo response, and highlighted a role for positive expectancy in predicting positive outcomes following psychedelic microdosing and cautions against zealous inferences on its putative therapeutic value.

TL;DR: Dynamic causal modelling revealed that both the presentation of novel stimuli and LSD modulate backward extrinsic connectivity within a task‐activated fronto‐temporal network, as well as intrinsic connectivity in the primary auditory cortex, suggesting an overall modulation of sensitivity to environmental stimuli.

TL;DR: Evidence is provided that LTP-based neural plasticity increases within the time frame of the antidepressant effects of ketamine in humans and supports the hypothesis that changes to neural Plasticity may be key to the antidepressant properties of ketamines.

TL;DR: This study presents the first evidence for the impact of self-reported levels of physical activity on LTP in humans, and sheds light on potential neurological mechanisms underlying the relationship between physical fitness and cognition.

TL;DR: The results suggest that both Predictive Coding and Hebbian mechanisms are utilized by the brain under different task demands, which indicates that both tasks provide unique insight into plasticity mechanisms, which has important implications for future studies of aberrant plasticity in clinical populations.