M
Megan Langille
Researcher at University of Southern California
Publications - 6
Citations - 96
Megan Langille is an academic researcher from University of Southern California. The author has contributed to research in topics: Multiple sclerosis & Age of onset. The author has an hindex of 4, co-authored 5 publications receiving 62 citations. Previous affiliations of Megan Langille include Children's Hospital Los Angeles & University of California, Los Angeles.
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Journal ArticleDOI
Radiologically isolated syndrome in children: Clinical and radiologic outcomes.
Naila Makhani,Christine Lebrun,Aksel Siva,David Brassat,Clarisse Carra Dallière,Jérôme De Seze,Wei Du,Francoise Durand Dubief,Orhun H. Kantarci,Megan Langille,Sona Narula,Jean Pelletier,Juan Ignacio Rojas,Eugene D. Shapiro,Robert Thompson Stone,Mar Tintoré,Ugur Uygunoglu,Patrick Vermersch,Evangeline Wassmer,Darin T. Okuda,Daniel Pelletier +20 more
TL;DR: Children with RIS had a substantial risk of subsequent clinical symptoms and/or radiologic evolution and the presence of oligoclonal bands in CSF and spinal cord lesions on MRI were associated with an increased risk of a first clinical event.
Journal ArticleDOI
Oligoclonal bands increase the specificity of MRI criteria to predict multiple sclerosis in children with radiologically isolated syndrome.
Naila Makhani,Christine Lebrun,Aksel Siva,Sona Narula,Evangeline Wassmer,David Brassat,J. Nicholas Brenton,Philippe Cabre,Clarisse Carra Dallière,Jérôme De Seze,Francoise Durand Dubief,Matilde Inglese,Megan Langille,Guillaume Mathey,Rinze F. Neuteboom,Jean Pelletier,Daniela Pohl,Daniel S. Reich,Juan Ignacio Rojas,Veronika Shabanova,Eugene D. Shapiro,Robert Thompson Stone,Silvia Tenembaum,Mar Tintoré,Ugur Uygunoglu,Wendy Vargas,Sunita Venkateswaren,Patrick Vermersch,Orhun H. Kantarci,Darin T. Okuda,Daniel Pelletier,Observatoire Francophone de la Sclérose en Plaques +31 more
TL;DR: Oligoclonal bands increased the specificity of magnetic resonance imaging criteria in children with Ped-RIS and Clinicians should consider testing cerebrospinal fluid to improve diagnostic certainty.
Journal ArticleDOI
Pediatric Multiple Sclerosis: A Review.
Journal ArticleDOI
Clinical Characteristics of Pediatric-Onset and Adult-Onset Multiple Sclerosis in Hispanic Americans
TL;DR: It is suggested that pediatric-onset multiple sclerosis and adult-onsets multiple sclerosis in Hispanics have differences that could be important for treatment and prognosis.
Journal Article
Comparison of MRI Dissemination in Space Criteria for Predicting a First Clinical Event in Children with the Radiologically Isolated Syndrome (S2.001)
Naila Makhani,Christine Lebrun,Aksel Siva,Sona Narula,Sona Narula,Evangeline Wassmer,J. Nicholas Brenton,Clarissa Carra Dalliere,Jérôme De Seze,Francoise Durand Dubief,Megan Langille,Megan Langille,Rinze F. Neuteboom,Jean Pelletier,Daniela Pohl,Daniela Pohl,Juan Ignacio Rojas,Eugene D. Shapiro,Robert Thompson Stone,Silvia Tenembaum,Mar Tintoré,Ugur Uygunoglu,Wendy Vargas,Orhun H. Kantarci,Darin T. Okuda,Daniel Pelletier,Observatoire Francophone de la Sclérose en Plaques,Société Francophone de la Sclérose en Plaques +27 more
TL;DR: Proposed MAGNIMS 2016 DIS criteria have greater sensitivity, but much lower specificity than 2005 DIS criteria for predicting a first clinical neurologic event in children with RIS-2010, and greater false positive diagnoses using 2016 criteria may generate clinical counseling concerns.