M
Mehdi Shakibaei
Researcher at Ludwig Maximilian University of Munich
Publications - 243
Citations - 14165
Mehdi Shakibaei is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Chondrocyte & Resveratrol. The author has an hindex of 65, co-authored 226 publications receiving 12065 citations. Previous affiliations of Mehdi Shakibaei include Free University of Berlin & Charité.
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Journal ArticleDOI
Mechanisms of magnesium-stimulated adhesion of osteoblastic cells to commonly used orthopaedic implants.
Hala Zreiqat,C. R. Howlett,Andrew C.W. Zannettino,Peter J. Evans,G. Schulze-Tanzil,C. Knabe,Mehdi Shakibaei +6 more
TL;DR: It is concluded that Mg(2+) supplementation of bioceramic substrata may be a promising way to improve integration of implants in orthopaedic and dental surgery.
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Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis.
TL;DR: Results indicate that curcumin has nutritional potential as a naturally occurring anti-inflammatory agent for treating OA through suppression of NF-kappaB mediated IL-1beta/TNF-alpha catabolic signalling pathways in chondrocytes.
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Resveratrol addiction: To die or not to die
TL;DR: While cell death is a hallmark of resveratrol, this polyphenol also has been linked with suppression of inflammation, arthritis, and cardiovascular diseases and delaying of aging.
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Glycosaminoglycan polymerization may enable osmotically inactive Na+ storage in the skin
Jens Titze,Mehdi Shakibaei,Markus Schafflhuber,Gundula Schulze-Tanzil,Markus Porst,Karl H. Schwind,Peter Dietsch,Karl F. Hilgers +7 more
TL;DR: It is concluded that osmotically inactive skin Na(+) storage is an active process characterized by an increased GAG content in the reservoir tissue, and inhibition or disinhibition of GAG chain polymerization may regulate osmOTically inactive Na(+ storage.
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Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis
TL;DR: Investigating the potential synergistic effects of curcumin and resveratrol on IL-1β-stimulated human chondrocytes in vitro proposes that combining these natural compounds may be a useful strategy in OA therapy as compared with separate treatment with each individual compound.