Mei Chi Cheung

TL;DR: A rapid gene-mapping system uses a high-resolution, dual-laser sorter to identify genes from separate human chromosomes prepared with a new stain combination to sort 21 unique chromosome types onto nitrocellulose filter papers.

TL;DR: The cDNA for human erythrocyte ankyrin has been isolated from a series of overlapping clones obtained from a reticulocyte cDNA library, and two cDNA clones showed evidence of apparent mRNA processing, resulting in deletions of 486 bp and 135 bp.

TL;DR: YACs have been constructed by a method that performs all steps in agarose, allowing size selection by pulsed-field gel electrophoresis and the use of nanogram to microgram quantities of DNA.

TL;DR: Simultaneous sorting of the normal homolog from this small derivative chromosome separated the two different sized insulin gene-containing restriction fragments in this individual, indicating that the two restriction fragments represent insulin gene polymorphism and not duplicate gene loci.

TL;DR: In order to map human PGKsequences, DNA was prepared from 55 human-mouse somatic cell lines and hybridized to flow-sorted chromosomes confirming the presence of PGK sequences on the X chromosome and chromosomes 6 and 19.