M
Melissa D. Mattocks
Researcher at University of North Carolina at Chapel Hill
Publications - 3
Citations - 161
Melissa D. Mattocks is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: CIRBP & Flaviviridae. The author has an hindex of 2, co-authored 3 publications receiving 66 citations.
Papers
More filters
Journal ArticleDOI
Altered m6A Modification of Specific Cellular Transcripts Affects Flaviviridae Infection
Nandan S. Gokhale,Alexa B. R. McIntyre,Melissa D. Mattocks,Christopher L. Holley,Helen M. Lazear,Christopher E. Mason,Stacy M. Horner +6 more
TL;DR: Analysis of the transcriptome following infection by dengue virus, Zika virus, West Nile virus, and hepatitis C virus found that infection by these viruses alters m6A modification of specific cellular transcripts, including RIOK3 and CIRBP.
Posted ContentDOI
Altered m6A modification of specific cellular transcripts affects Flaviviridae infection
Nandan S. Gokhale,Alexa B. R. McIntyre,Melissa D. Mattocks,Christopher L. Holley,Helen M. Lazear,Christopher E. Mason,Stacy M. Horner +6 more
TL;DR: This work reveals that cellular signaling pathways activated during viral infection lead to alterations in m6A modification of host mRNAs to regulate infection.
Posted ContentDOI
Zika virus infection in Collaborative Cross mice
Melissa D. Mattocks,Kenneth S. Plante,Ethan J. Fritch,Ralph S. Baric,Martin T. Ferris,Mark T. Heise,Helen M. Lazear +6 more
TL;DR: Collaborative Cross mice have proven to be a valuable system for developing new mouse pathogenesis models for viral infections that are not well modeled in conventional laboratory mouse lines, and it is suggested that the tested CC lines do not include polymorphic host genes that greatly increase susceptibility to ZIKV infection.