M
Mengfang Yang
Researcher at Huazhong Agricultural University
Publications - 4
Citations - 11
Mengfang Yang is an academic researcher from Huazhong Agricultural University. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 1, co-authored 1 publications receiving 1 citations.
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Journal ArticleDOI
The structural basis of African swine fever virus core shell protein p15 binding to DNA.
Fenglin Guo,Yuejun Shi,Mengfang Yang,Yilin Guo,Zhou Shen,Mengxia Li,Yixi Chen,Rui Liang,Yilin Yang,Huanchun Chen,Guiqing Peng +10 more
TL;DR: In this article, the ASFV core shell protein p15 has been resolved and the secondary structural elements of a protomer include four α-helix structures and six antiparallel β-strands.
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Adaptive Mutation in the Main Protease Cleavage Site of Feline Coronavirus Renders the Virus More Resistant to Main Protease Inhibitors
Zhe Jiao,Yuanyuan Yan,Yixi Chen,Gang Wang,Xiaowei Wang,Lisha Li,Mengfang Yang,Xiaoshuai Hu,Yilin Guo,Yuejun Shi,Guiqing Peng +10 more
TL;DR: The research explains the evolutionary characteristics of coronaviruses under antiviral drugs, which is helpful for a more comprehensive understanding of the molecular basis of virus resistance and provides important basic data for the effective prevention and control of CoVs.
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Safety and immunogenicity of a TK/ gI/gE gene-deleted feline herpesvirus-1 mutant constructed via CRISPR/Cas9 in feline.
Mengfang Yang,Yuzhou Jiao,Yuanyuan Yan,Lisha Li,Xiaoshuai Hu,Zhe Jiao,Mengxia Li,Yixi Chen,Yuejun Shi,Zhou Shen,Guiqing Peng +10 more
TL;DR: In this article , the authors constructed a novel TK/gI/gE -gene-deleted recombinant FHV-1 (WH2020-ΔTK/GI/GE) through CRISPR/Cas9-mediated homologous recombination.
Journal ArticleDOI
Better therapeutic effect of oral administration of GS441524 compared with GC376.
Yuanyuan Yan,Zhe Jiao,Mengfang Yang,Gang Wang,Yixi Chen,Mengxia Li,Zhou Shen,Yuejun Shi,Gui-zu Peng +8 more
TL;DR: In this paper , two drugs (GS441524 and GC376) target FIPV and have good therapeutic effect when administered by subcutaneous injection, however, the oral efficacy of the two drugs has not been determined.