Mercedes Fernández-Mestre

TL;DR: Preliminary ultrastructural studies with the most active complex at 1 h revealed parasite swelling and binucleated cells, which suggests that the leishmanicidal activity of the copper complexes could be associated with their interaction with the parasitic DNA.

TL;DR: This work describes single-nucleotide polymorphism of tumor necrosis factor (TNF)-alpha, interferon-gamma, interleukin (IL)-6, transforming growth factor-beta1, and IL-10 in patients with dengue virus infections and analyzes their relation with clinical manifestations of the disease.

TL;DR: The results indicate that the polymorphism of CTLA-4 is an important genetic factor associated with risk or protection for the development of diffuse cutaneous leishmaniasis and has influence in the pathogenesis of autoimmune diseases.

TL;DR: Preliminary studies of the ultrastructure of L. mexicana treated with a sublethal dose of the title complex showed an induction of cytoplasm disorganization, vacuolization and binucleated cells, suggesting that the leishmanicidal activity of theTitle complex could be associated with its interaction with the parasitic DNA.

TL;DR: Type 1 AIH is a progressive liver disease characterized by the presence of circulating autoantibodies, hypergammaglobulinaemia and a favourable response to immunosuppressive treatment and disease susceptibility is partially determined by genes linked to the class II region of the major histocompatibility complex.