Journal of Inorganic Biochemistry 

TL;DR: The preclinical and early clinical development of KP1019 - from bench to bedside - is recapitulated and promising activity against certain types of tumors is observed.

TL;DR: Cadmium inhalation in rats results in pulmonary adenocarcinomas, supporting a role in human lung cancer, and various treatments can modify cadmium carcinogenesis including supplemental zinc, which prevents Cadmium-induced injection site and testicular tumors while facilitating prostatic tumors.

TL;DR: Details are provided of the stoichiometric transformation through which nitric oxide is converted to nitrate with accompanying oxidation of myoglobin or hemoglobin to the corresponding iron(III) hemoprotein, including an estimate of the rate constant.

TL;DR: Accumulated evidence shows that the ferryl species [Fe(IV)O](2+) can be formed under a variety of conditions including those related to the ferrous ion-hydrogen peroxide system known as Fenton's reagent, indicating that the oxygen rebound pathway is a ubiquitous mechanism for hydrocarbon oxygenation by both heme and non-heme iron enzymes.

TL;DR: The toxicity of iron in specific tissues and cell types (liver, macrophages and brain) is illustrated by studies with appropriate cellular and animal models and the prospects for chelation therapy in the treatment and possible prevention of neurodegenerative diseases is reviewed.