M
Meritxell Pons
Researcher at Pompeu Fabra University
Publications - 1
Citations - 232
Meritxell Pons is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: Trisomy & DYRK1A. The author has an hindex of 1, co-authored 1 publications receiving 210 citations.
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Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans
Rafael de la Torre,Susana Solá,Meritxell Pons,Arnaud Duchon,María Martínez de Lagrán,Magí Farré,Montserrat Fitó,Bessy Benejam,Klaus Langohr,Joan Rodríguez,Mitona Pujadas,Jean Charles Bizot,Aida Cuenca,Nathalie Janel,Silvina Catuara,María Isabel Covas,Henri Bléhaut,Yann Herault,Jean M. Delabar,Mara Dierssen +19 more
TL;DR: EGCG is a promising therapeutic tool for cognitive enhancement in DS, and its efficacy may depend of Dyrk1A inhibition, and plasma homocysteine levels are used as an efficacy biomarker in the human study.