M
Mewahyu Dewi
Researcher at Eijkman Institute for Molecular Biology
Publications - 7
Citations - 1454
Mewahyu Dewi is an academic researcher from Eijkman Institute for Molecular Biology. The author has contributed to research in topics: Malaria & Plasmodium vivax. The author has an hindex of 6, co-authored 7 publications receiving 1178 citations.
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Journal ArticleDOI
Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates.
Frédéric B. Piel,Anand P. Patil,Rosalind E. Howes,Oscar A. Nyangiri,Peter W. Gething,Mewahyu Dewi,William H. Temperley,Thomas N. Williams,Thomas N. Williams,David J. Weatherall,Simon I. Hay +10 more
TL;DR: These estimates can help countries and the international community gauge the need for appropriate diagnoses and genetic counselling to reduce the number of neonates affected by HbS and could be used for other inherited disorders.
Journal ArticleDOI
G6PD deficiency prevalence and estimates of affected populations in malaria endemic countries: a geostatistical model-based map.
Rosalind E. Howes,Frédéric B. Piel,Anand P. Patil,Oscar A. Nyangiri,Peter W. Gething,Mewahyu Dewi,Mariana M. Hogg,Katherine E. Battle,Carmencita Padilla,Carmencita Padilla,J. Kevin Baird,Simon I. Hay +11 more
TL;DR: A map of glucose-6-phosphate dehydrogenase deficiency prevalence and severity is presented and individuals with the deficiency are at risk of mild to severe hemolysis when taking the antimalarial primaquine.
Journal ArticleDOI
Spatial distribution of G6PD deficiency variants across malaria-endemic regions
Rosalind E. Howes,Mewahyu Dewi,Frédéric B. Piel,Wuelton Marcelo Monteiro,Katherine E. Battle,Jane P. Messina,Anavaj Sakuntabhai,Ari W. Satyagraha,Thomas N. Williams,Thomas N. Williams,J K Baird,Simon I. Hay +11 more
TL;DR: G6PD variants exhibited distinctive region-specific distributions with important primaquine policy implications, and relative homogeneity in the Americas, Africa, and western Asia contrasted sharply with the heterogeneity of variants in China, Southeast Asia and Oceania.
Journal ArticleDOI
Noninferiority of glucose-6-phosphate dehydrogenase deficiency diagnosis by a point-of-care rapid test vs the laboratory fluorescent spot test demonstrated by copper inhibition in normal human red blood cells
TL;DR: A new point-of-care G6PD screening kit may vastly expand access to primaquine therapy and aid in mitigating the very substantial burden of morbidity and mortality imposed by the hypnozoite reservoir of vivax malaria.
Journal Article
Detection of beta-globin gene mutations among Kelantan Malay thalassaemia patients by polymerase chain reaction restriction fragment length polymorphism.
R Rozitah,M. Z. Nizam,A R Nur Shafawati,M A Nor Atifah,Mewahyu Dewi,Thirumulu Ponnuraj Kannan,N Ariffin,M Norsarwany,Iswari Setianingsih,Alida Harahap,Bin Alwi Zilfalil +10 more
TL;DR: The results added to the existing data on the common beta-globin gene defects in Kelantan Malay beta-thalassaemia patients.