M
MF McLane
Researcher at Harvard University
Publications - 30
Citations - 3723
MF McLane is an academic researcher from Harvard University. The author has contributed to research in topics: Virus & Antigen. The author has an hindex of 23, co-authored 30 publications receiving 3688 citations. Previous affiliations of MF McLane include Emory University & Centers for Disease Control and Prevention.
Papers
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Journal ArticleDOI
Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III
James S. Allan,John E. Coligan,F Barin,MF McLane,Joseph Sodroski,Craig A. Rosen,William A. Haseltine,Tak H. Lee,Myron Essex +8 more
TL;DR: It is hypothesized that gp160 and gp120 represent the major species of virus-encoded envelope gene products for HTLV-III.
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Antibodies to cell membrane antigens associated with human T-cell leukemia virus in patients with AIDS
Myron Essex,MF McLane,Tak H. Lee,Lawrence A. Falk,C. W. S. Howe,James I. Mullins,C. Cabradilla,Donald P. Francis +7 more
TL;DR: Serum samples from patients with AIDS and from matched and unmatched control subjects were examined for the presence of antibodies to cell membrane antigens associated with human T-cell leukemia virus.
Journal ArticleDOI
New human T-lymphotropic retrovirus related to simian T-lymphotropic virus type III (STLV-IIIAGM).
Phyllis J. Kanki,Francis Barin,Souleymane Mboup,James S. Allan,Jean-Loup Romet-Lemonne,Richard Marlink,MF McLane,Tak H. Lee,B Arbeille,François Denis +9 more
TL;DR: Serologic data suggest that this virus shares more common epitopes with STLV-IIIAGM than with the prototype HTLV-III/LAV that infects people in the United States and Europe, and may expand the understanding of the human AIDS virus.
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Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients.
TL;DR: Two glycoproteins that are encoded by human T-cell lymphoma virus type III (HTLV-III) were the antigens most consistently recognized by antibodies found in patients with the acquired immune deficiency syndrome (AIDS) and with the AIDS-related complex (ARC) and in healthy homosexual males.
Journal ArticleDOI
Serologic identification and characterization of a macaque T-lymphotropic rétrovirus closely related to HTLV-III
Phyllis J. Kanki,MF McLane,Norval W. King,Norman L. Letvin,R. D. Hunt,Prabhat K. Sehgal,Muthiah D. Daniel,Ronald C. Desrosiers,Myron Essex +8 more
TL;DR: The serologic characterization of a new simian retrovirus that is related to HTLV-III is described, which naturally infects a nonhuman primate species and may provide a useful model for the study of HT LV-III and the pathogenesis of AIDS.