M
Michael B. Ellman
Researcher at Rush University Medical Center
Publications - 59
Citations - 2891
Michael B. Ellman is an academic researcher from Rush University Medical Center. The author has contributed to research in topics: Cartilage & Cartilage homeostasis. The author has an hindex of 27, co-authored 59 publications receiving 2463 citations. Previous affiliations of Michael B. Ellman include University of Illinois at Chicago.
Papers
More filters
Journal ArticleDOI
Meniscal Root Tears: Significance, Diagnosis, and Treatment
TL;DR: This article presents a review of the clinically relevant anatomic, biomechanical, and functional descriptions of the meniscus root attachments, as well as current strategies for accurate diagnosis and treatment of common injuries to these meniscal root attachments.
Journal ArticleDOI
A current review of molecular mechanisms regarding osteoarthritis and pain
Andrew S. Lee,Michael B. Ellman,Dongyao Yan,Jeffrey S. Kroin,Brian J. Cole,Andre J. van Wijnen,Hee Jeong Im +6 more
TL;DR: Several biochemical mediators involved in OA and pain are explored, and a framework for the understanding of potential biologic therapies in the treatment of degenerative joint disease in the future is provided.
Journal ArticleDOI
Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis.
TL;DR: The results from in vitro and in vivo studies suggest the potential usefulness of bFGF and FGFR1 antagonists, as well as FGF-18 andFGFR3 agonists, as potential therapies to prevent cartilage degeneration and/or promote cartilage regeneration and repair in the future.
Journal ArticleDOI
Fibroblast growth factor control of cartilage homeostasis
TL;DR: The available evidence reveals the promise of FGF‐2/FGFR1 antagonists, F GF‐18/FG FR3 agonists, and FGF•8 antagonists as potential therapies to prevent cartilage degeneration and/or promote cartilage regeneration and repair in the future.
Journal ArticleDOI
Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis
Xin Li,Michael B. Ellman,Prasuna Muddasani,James H.-C. Wang,Gabriella Cs-Szabo,Andre J. Van Wijnen,Hee Jeong Im +6 more
TL;DR: PGE(2) exerts an antianabolic effect on human adult articular cartilage in vitro, and EP2 and EP4 receptor antagonists may represent effective therapeutic agents for the treatment of OA.