M
Michael Brownlee
Researcher at JDRF
Publications - 4
Citations - 1181
Michael Brownlee is an academic researcher from JDRF. The author has contributed to research in topics: Diabetes mellitus & Regulation of gene expression. The author has an hindex of 4, co-authored 4 publications receiving 992 citations.
Papers
More filters
Journal ArticleDOI
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
Assam El-Osta,Daniella Brasacchio,Dachun Yao,Alessandro Pocai,Peter L. Jones,Robert G. Roeder,Mark E. Cooper,Mark E. Cooper,Michael Brownlee +8 more
TL;DR: It is shown that transient hyperglycemia induces long-lasting activating epigenetic changes in the promoter of the nuclear factor κB subunit p65 in aortic endothelial cells both in vitro and in nondiabetic mice, which cause increased p65 gene expression.
Journal ArticleDOI
Correction: Diabetic kidney disease
Merlin C. Thomas,Michael Brownlee,Katalin Susztak,Kumar Sharma,Karin Jandeleit-Dahm,Sophia Zoungas,Peter Rossing,Per-Henrik Groop,Mark E. Cooper +8 more
TL;DR: This analysis was conducted using participants from Asia, and it is shown that the DEMAND study with 2,862 participants was conducted in an Indigenous Australian population.