M
Michael E. Trautmann
Researcher at Eli Lilly and Company
Publications - 51
Citations - 7665
Michael E. Trautmann is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Exenatide & Diabetes mellitus. The author has an hindex of 34, co-authored 50 publications receiving 7378 citations. Previous affiliations of Michael E. Trautmann include Amylin Pharmaceuticals.
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Journal ArticleDOI
Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study.
Daniel J. Drucker,John B. Buse,Kristin Taylor,David M. Kendall,Michael E. Trautmann,Dongliang Zhuang,Lisa Porter +6 more
TL;DR: Exen atide once weekly resulted in significantly greater improvements in glycaemic control than exenatide given twice a day, with no increased risk of hypoglycaemia and similar reductions in bodyweight.
Journal ArticleDOI
A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a non-inferiority study.
M. A. Nauck,S. Duran,Dennis Kim,Don Johns,Justin Northrup,Andreas Festa,R. Brodows,Michael E. Trautmann +7 more
TL;DR: Exenatide treatment resulted in HbA1c reduction similar to biphasic insulin aspart and provided better postprandial glycaemic control, making it a potential alternative for the treatment of type 2 diabetes.
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The effect of adding exenatide to a thiazolidinedione in suboptimally controlled type 2 diabetes: a randomized trial.
Bernard Zinman,Byron J. Hoogwerf,Santiago Durán García,Denái R. Milton,Joseph M Giaconia,Dennis Dong Hwan Kim,Michael E. Trautmann,R. Brodows +7 more
TL;DR: In this article, the effect of adding exenatide to several oral hypoglycemic drugs in patients with poorly controlled type 2 diabetes has been studied and no one has studied the addition of exenate in clinical trials.
Journal ArticleDOI
Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial
Michaela Diamant,Luc Van Gaal,Stephen N Stranks,Justin Northrup,Dachuang Cao,Kristin Taylor,Michael E. Trautmann +6 more
TL;DR: Once weekly exenatide is an important therapeutic option for patients for whom risk of hypoglycaemia, weight loss, and convenience are particular concerns, and this trial aimed to test the hypothesis that improvement in haemoglobin A(1c) (HbA( 1c))) achieved with once weekly exanatide was superior to that achieved with insulin glargine titrated to glucose targets.
Journal ArticleDOI
Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
L. Blonde,E. J. Klein,Jenny Han,B. Zhang,S. M. Mac,T. H. Poon,Kristin Taylor,Michael E. Trautmann,Dennis Kim,D. M. Kendall +9 more
TL;DR: Exenatide, an incretin mimetic for the adjunct treatment of type 2 diabetes (DM2), reduced A1C and weight in 30‐week placebo‐controlled trials in patients unable to achieve adequate glycaemic control with sulphonylurea and/or metformin.