Showing papers by "Michael F. Hirshman published in 2011"
TL;DR: Exercise and weight loss are cornerstones in the treatment and prevention of type 2 diabetes, and both interventions function to increase insulin sensitivity and glucose uptake into skeletal muscle, but surprisingly, there was no effect on expression or phosphorylation of any of the muscle-signaling proteins.
Abstract: Exercise and weight loss are cornerstones in the treatment and prevention of type 2 diabetes, and both interventions function to increase insulin sensitivity and glucose uptake into skeletal muscle...
59 citations
TL;DR: Myo1c is a novel mediator of both insulin-stimulated and contraction- Stimulated glucose uptake in skeletal muscle and neither wild-type nor K111A-Myo 1c expression altered GLUT4 expression, and neither affected contraction- or insulin- stimulated signaling proteins.
50 citations