J
Jonas Nygren
Researcher at Karolinska Institutet
Publications - 135
Citations - 13135
Jonas Nygren is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Insulin resistance & Insulin. The author has an hindex of 50, co-authored 131 publications receiving 11821 citations. Previous affiliations of Jonas Nygren include Stockholm University & Karolinska University Hospital.
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Journal ArticleDOI
Enhanced recovery after surgery : a consensus review of clinical care for patients undergoing colonic resection
Kenneth C. H. Fearon,Olle Ljungqvist,M.F. von Meyenfeldt,Arthur Revhaug,Cornelis H. C. Dejong,Kristoffer Lassen,Jonas Nygren,Jonatan Hausel,Mattias Soop,Jens Rikardt Andersen,Henrik Kehlet +10 more
TL;DR: In this article, clinical care of patients undergoing colonic surgery differs between hospitals and countries, and there is considerable variation in rates of recovery and length of colon cancer surgery in different countries.
Journal ArticleDOI
Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations.
Kristoffer Lassen,Mattias Soop,Jonas Nygren,P. Boris W. Cox,P. O. Hendry,Claudia Spies,Maarten F. von Meyenfeldt,Kenneth C. H. Fearon,Arthur Revhaug,Stig Norderval,Olle Ljungqvist,Dileep N. Lobo,Cornelis H. C. Dejong +12 more
TL;DR: The Enhanced Recovery After Surgery (ERAS) Group presents a comprehensive evidence-based consensus review of perioperative care for colorectal surgery based on the evidence available for each element of the multimodal peri operative care pathway.
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Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes.
Nicolas Musi,Michael F. Hirshman,Jonas Nygren,Monika Svanfeldt,Peter Båvenholm,Olav Rooyackers,Gaochao Zhou,Joanne M. Williamson,Olle Ljunqvist,Suad Efendic,David E. Moller,Anders Thorell,Laurie J. Goodyear +12 more
TL;DR: The findings suggest that the metabolic effects of metformin in subjects with type 2 diabetes may be mediated by the activation of AMPK alpha2, which is implicated in the stimulation of glucose uptake into skeletal muscle and the inhibition of liver gluconeogenesis.
Journal ArticleDOI
Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery.
TL;DR: Improved adherence to the standardized multimodal ERAS protocol is significantly associated with improved clinical outcomes following major colorectal cancer surgery, indicating a dose-response relationship.
Journal ArticleDOI
The Impact of Enhanced Recovery Protocol Compliance on Elective Colorectal Cancer Resection Results From an International Registry
Andrew Currie,Jennifer Burch,John T. Jenkins,Omar Faiz,R Kennedy,Olle Ljungqvist,Nicolas Demartines,Fredrik Hjern,Stig Norderval,Kristoffer Lassen,Andarthur Revhaug,Tomas Koczkas,Jonas Nygren,Ulf Gustafsson,Dan Kornfeld,Karem Slim,Andrew G. Hill,Mattias Soop,Johan Carlander,Owe Lundberg,Kenneth C. H. Fearon,Robin H. Kennedy +21 more
TL;DR: It is demonstrated that in a large, international cohort of patients, increasing compliance with an ERAS program and the use of laparoscopic surgery independently improve outcome.