M
Michael J. Meaney
Researcher at Agency for Science, Technology and Research
Publications - 669
Citations - 87378
Michael J. Meaney is an academic researcher from Agency for Science, Technology and Research. The author has contributed to research in topics: Offspring & Medicine. The author has an hindex of 136, co-authored 604 publications receiving 81128 citations. Previous affiliations of Michael J. Meaney include Emory University & Rockefeller University.
Papers
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Journal ArticleDOI
Epigenetic programming by maternal behavior.
Ian C. G. Weaver,Nadia Cervoni,Frances A. Champagne,Ana C. D'Alessio,Shakti Sharma,Jonathan R. Seckl,Sergiy Dymov,Moshe Szyf,Michael J. Meaney +8 more
TL;DR: It is shown that an epigenomic state of a gene can be established through behavioral programming, and it is potentially reversible, suggesting a causal relation among epigenomicState, GR expression and the maternal effect on stress responses in the offspring.
Journal ArticleDOI
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
Patrick O. McGowan,Aya Sasaki,Aya Sasaki,Ana C. D'Alessio,Sergiy Dymov,Benoit Labonté,Moshe Szyf,Gustavo Turecki,Michael J. Meaney,Michael J. Meaney +9 more
TL;DR: Findings translate previous results from rat to humans and suggest a common effect of parental care on the epigenetic regulation of hippocampal glucocorticoid receptor expression.
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Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress
Dong Liu,Josie Diorio,Josie Diorio,Beth Tannenbaum,Beth Tannenbaum,Christian Caldji,Christian Caldji,Darlene D. Francis,Darlene D. Francis,Alison Freedman,Alison Freedman,Shakti Sharma,Shakti Sharma,Deborah Pearson,Deborah Pearson,Paul M. Plotsky,Paul M. Plotsky,Michael J. Meaney,Michael J. Meaney +18 more
TL;DR: It is suggested that maternal behavior serves to "program" hypothalamic-pituitary-adrenal responses to stress in the offspring.
Journal ArticleDOI
Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations.
TL;DR: Evidence is provided for the importance of parental care as a mediator of the effects of environmental adversity on neural development and patterns of maternal care that increase stress reactivity in offspring are enhanced by stressors imposed on the mother.
Journal ArticleDOI
Nongenomic Transmission Across Generations of Maternal Behavior and Stress Responses in the Rat
TL;DR: Results of cross-fostering studies reported here indicate that variations in maternal care can serve as the basis for a nongenomic behavioral transmission of individual differences in stress reactivity across generations.